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dc.contributor.authorManceau, M
dc.contributor.authorDomingues, V. S.
dc.contributor.authorLinnen, Catherine Ramsay
dc.contributor.authorRosenblum, E. B.
dc.contributor.authorHoekstra, Hopi E.
dc.date.accessioned2018-01-24T17:24:23Z
dc.date.issued2010
dc.identifierQuick submit: 2014-07-12T11:11:54-04:00
dc.identifier.citationManceau, M., V. S. Domingues, C. R. Linnen, E. B. Rosenblum, and H. E. Hoekstra. 2010. Convergence in Pigmentation at Multiple Levels: Mutations, Genes and Function. Philosophical Transactions of the Royal Society B: Biological Sciences 365, no. 1552: 2439–2450. doi:10.1098/rstb.2010.0104.en_US
dc.identifier.issn0962-8436en_US
dc.identifier.urihttp://nrs.harvard.edu/urn-3:HUL.InstRepos:34728583
dc.description.abstractConvergence—the independent evolution of the same trait by two or more taxa—has long been of interest to evolutionary biologists, but only recently has the molecular basis of phenotypic convergence been identified. Here, we highlight studies of rapid evolution of cryptic coloration in vertebrates to demonstrate that phenotypic convergence can occur at multiple levels: mutations, genes and gene function. We first show that different genes can be responsible for convergent phenotypes even among closely related populations, for example, in the pale beach mice inhabiting Florida's Gulf and Atlantic coasts. By contrast, the exact same mutation can create similar phenotypes in distantly related species such as mice and mammoths. Next, we show that different mutations in the same gene need not be functionally equivalent to produce similar phenotypes. For example, separate mutations produce divergent protein function but convergent pale coloration in two lizard species. Similarly, mutations that alter the expression of a gene in different ways can, nevertheless, result in similar phenotypes, as demonstrated by sister species of deer mice. Together these studies underscore the importance of identifying not only the genes, but also the precise mutations and their effects on protein function, that contribute to adaptation and highlight how convergence can occur at different genetic levels.en_US
dc.description.sponsorshipOrganismic and Evolutionary Biologyen_US
dc.language.isoen_USen_US
dc.publisherThe Royal Societyen_US
dc.relation.isversionofdoi:10.1098/rstb.2010.0104en_US
dash.licenseMETA_ONLY
dc.titleConvergence in pigmentation at multiple levels: mutations, genes and functionen_US
dc.typeJournal Articleen_US
dc.date.updated2014-07-12T15:11:55Z
dc.description.versionVersion of Recorden_US
dc.rights.holderManceau, M., V.S Domingues, C.R. Linnen, E.B. Rosenblum and H.E. Hoekstra
dc.relation.journalPhilosophical Transactions of the Royal Society B: Biological Sciencesen_US
dash.depositing.authorHoekstra, Hopi E.
dash.embargo.until10000-01-01
dc.identifier.doi10.1098/rstb.2010.0104*
workflow.legacycommentsoap.needman (MM) Hoekstra emailed 2016-05-15 MM Hoekstra emailed 2017-03-02 MMen_US
dash.contributor.affiliatedManceau, Marie
dash.contributor.affiliatedHoekstra, Hopi
dash.contributor.affiliatedLinnen, Catherine


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