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dc.contributor.authorNielsen-Marsh, Christina M.
dc.contributor.authorStegemann, Christin
dc.contributor.authorHoffmann, Ralf
dc.contributor.authorSmith, Tanya
dc.contributor.authorFeeney, Robin
dc.contributor.authorToussaint, Michel
dc.contributor.authorHarvati, Katerina
dc.contributor.authorPanagopoulou, Eleni
dc.contributor.authorHublin, Jean-Jacques
dc.contributor.authorRichards, Michael P.
dc.date.accessioned2018-01-24T18:11:50Z
dc.date.issued2009
dc.identifier.citationNielsen-Marsh, Christina M., Christin Stegemann, Ralf Hoffmann, Tanya Smith, Robin Feeney, Michel Toussaint, Katerina Harvati, Eleni Panagopoulou, Jean-Jacques Hublin, and Michael P. Richards. 2009. “Extraction and Sequencing of Human and Neanderthal Mature Enamel Proteins Using MALDI-TOF/TOF MS.” Journal of Archaeological Science 36 (8) (August): 1758–1763. doi:10.1016/j.jas.2009.04.004.en_US
dc.identifier.issn0305-4403en_US
dc.identifier.urihttp://nrs.harvard.edu/urn-3:HUL.InstRepos:34728632
dc.description.abstractWe report here the first results of a method to extract and sequence mature enamel proteins from modern human and Neanderthal tooth enamel. Using MALDI-TOF/TOF mass spectrometry and a combination of direct sequencing and peptide mass mapping we have sequenced a peptide from the tyrosine-rich amelogenin peptide (TRAP) of the X isoform of the amelogenin protein for modern and recent human samples. We also report our results from two Neanderthal enamel samples where we were also able to recover fragments of the TRAP protein, which had a similar sequence to the modern human samples.en_US
dc.description.sponsorshipOrganismic and Evolutionary Biologyen_US
dc.language.isoen_USen_US
dc.publisherElsevier BVen_US
dc.relation.isversionofdoi:10.1016/j.jas.2009.04.004en_US
dash.licenseMETA_ONLY
dc.subjectProteomicsen_US
dc.subjectEnamelen_US
dc.subjectNeanderthalen_US
dc.subjectMALDI-TOF-TOFen_US
dc.titleExtraction and sequencing of human and Neanderthal mature enamel proteins using MALDI-TOF/TOF MSen_US
dc.typeJournal Articleen_US
dc.description.versionVersion of Recorden_US
dc.relation.journalJournal of Archaeological Scienceen_US
dash.depositing.authorSmith, Tanya
dash.embargo.until10000-01-01
dc.identifier.doi10.1016/j.jas.2009.04.004*
workflow.legacycommentsFAR 2010 Smith emailed 2016-04-22 MM Smith emailed 2017-02-20 MM noap.needmanen_US
dash.contributor.affiliatedSmith, Tanya


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