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dc.contributor.authorMaffoni, S.
dc.contributor.authorDe Giuseppe, R.
dc.contributor.authorF.C., Stanford
dc.contributor.authorCena, H.
dc.contributor.authorStanford, Fatima Cody
dc.date.accessioned2018-02-20T16:43:28Z
dash.embargo.terms2018-12-01
dc.date.issued2017
dc.identifierQuick submit: 2017-09-18T11:56:39-0400
dc.identifier.citationMaffoni, Silvia, Rachele De Giuseppe, Fatima Cody Stanford, and Hellas Cena. 2017. “Folate Status in Women of Childbearing Age with Obesity: a Review.” Nutrition Research Reviews 30 (02) (June 7): 265–271. doi:10.1017/s0954422417000142.en_US
dc.identifier.issn0954-4224en_US
dc.identifier.urihttp://nrs.harvard.edu/urn-3:HUL.InstRepos:34853257
dc.description.abstractSeveral studies have described a positive association between elevated BMI and birth defects risk. Data on plasma concentration of folate in pregnant women with obesity have shown values far below those recommended, regardless of diet, while folate levels should increase before pregnancy to reduce neural tube defects. We report a descriptive review of the most recent studies (from 2005 to 2015) to evaluate folate status through a population of women of childbearing age affected by obesity. The literature contains few studies, which present conflicting results regarding folate status in non-pregnant women of childbearing age affected by obesity, and it appears that there is a modification in folate metabolism, with a reduction in plasma folate levels and an increase in erythrocyte folate uptake. In conclusion, the folate status in women of childbearing age should be assessed by both plasma and erythrocyte levels to start a personalised and more adequate supplementation before conception. Further studies need to be conducted in a larger population, which take into account variables that can affect folate metabolism, such as dietary intake, lifestyle and genetic factors, oral contraceptives or other drug use, previous weight-loss programmes, or a history of bariatric surgery.en_US
dc.language.isoen_USen_US
dc.publisherCambridge University Press (CUP)en_US
dc.relation.isversionof10.1017/S0954422417000142en_US
dash.licenseLAA
dc.titleFolate status in women of childbearing age with obesity: a reviewen_US
dc.typeJournal Articleen_US
dc.date.updated2017-09-18T15:56:44Z
dc.description.versionVersion of Recorden_US
dc.relation.journalNutrition Research Reviewsen_US
dash.depositing.authorStanford, Fatima Cody
dash.embargo.until2018-12-01
dc.date.available2017
dc.identifier.doi10.1017/S0954422417000142*
dash.authorsorderedfalse
dash.contributor.affiliatedStanford, Fatima


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