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dc.contributor.authorSaboo, Ujwala S.
dc.contributor.authorAmparo, Francisco
dc.contributor.authorShikari, Hasanain
dc.contributor.authorJurkunas, Ula V.
dc.contributor.authorDana, Reza
dc.date.accessioned2018-02-20T21:41:21Z
dc.date.issued2015
dc.identifierQuick submit: 2017-06-18T21:34:18-0400
dc.identifier.citationSaboo, Ujwala S., Francisco Amparo, Hasanain Shikari, Ula V. Jurkunas, and Reza Dana. 2015. “Outcomes of Phacoemulsification in Patients with Chronic Ocular Graft-Versus-Host Disease.” Graefe’s Archive for Clinical and Experimental Ophthalmology 253 (6) (January 27): 901–907. doi:10.1007/s00417-015-2940-3.en_US
dc.identifier.issn0721-832Xen_US
dc.identifier.urihttp://nrs.harvard.edu/urn-3:HUL.InstRepos:34854274
dc.description.abstractPurpose To evaluate the outcomes of phacoemulsification in patients with ocular graft-versus-host disease (GVHD). Methods The occurrence of cataract, cataract surgery and its outcomes were analyzed in the medical records of 229 patients (458 eyes) with ocular GVHD. Outcome measures included pre- and postoperative corrected distance visual acuity (CDVA) and the rate of postoperative complications. Results From 458 eyes evaluated 58 were pseudophakic, from the 400 phakic eyes 238 (59%) presented with cataracts and 62 (26%) underwent cataract surgery. Analysis of postoperative complications and visual outcomes at one month was performed in 51 eyes in which detailed surgical and immediate postoperative records were available. Preoperatively, the mean CDVA was 0.67±0.57 LogMAR (Snellen 20/93) and improved postoperatively to 0.17±0.18 (Snellen 20/29) at one month (P<0.0001), and to 0.13±0.14 (Snellen 20/26) by the final follow-up visit (P<0.0001). Postoperative complications included: corneal epithelial defects (8%), filamentary keratitis (6%), worsening of corneal epitheliopathy (16%), posterior capsular opacification (18%), and cystoid macular edema (4%). A corrected distance visual acuity of 20/30 or better was achieved in 87% of the eyes; suboptimal CDVA improvement was accounted by severe ocular surface disease, pre-existing advanced glaucoma, and prior macular surgery. Conclusions Phacoemulsification in patients with chronic ocular GVHD is a safe and efficacious procedure resulting in significant visual improvement. Overall, postoperative adverse events responded well to timely management.en_US
dc.language.isoen_USen_US
dc.publisherSpringer Natureen_US
dc.relation.isversionof10.1007/s00417-015-2940-3en_US
dc.relation.hasversionhttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC4447562/en_US
dash.licenseOAP
dc.titleOutcomes of phacoemulsification in patients with chronic ocular graft-versus-host diseaseen_US
dc.typeJournal Articleen_US
dc.date.updated2017-06-19T01:34:20Z
dc.description.versionAccepted Manuscripten_US
dc.relation.journalGraefe's Archive for Clinical and Experimental Ophthalmologyen_US
dash.depositing.authorDana, Reza
dc.date.available2015
dc.date.available2018-02-20T21:41:21Z
dc.identifier.doi10.1007/s00417-015-2940-3*
workflow.legacycommentscat.complete cfr.complete (clc)en_US
dash.contributor.affiliatedJurkunas, Ula
dash.contributor.affiliatedDana, Reza


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