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dc.contributor.authorGiovanello, Kelly S.
dc.contributor.authorKensinger, Elizabeth A
dc.contributor.authorWong, Alana T.
dc.contributor.authorSchacter, Daniel L.
dc.date.accessioned2010-02-05T19:18:51Z
dash.embargo.terms2011-07-01
dc.date.issued2010
dc.identifier.citationGiovanello, Kelly S., Elizabeth A. Kensinger, Alana T. Wong, and Daniel L. Schacter. Forthcoming. Aged-related neural changes during memory conjunction errors. Journal of Cognitive Neuroscience 22.en_US
dc.identifier.issn0898-929Xen_US
dc.identifier.urihttp://nrs.harvard.edu/urn-3:HUL.InstRepos:3627273
dc.description.abstractHuman behavioral studies demonstrate that healthy aging is often accompanied by increases in memory distortions or errors. Here we used event-related functional MRI to examine the neural basis of age-related memory distortions. We used the memory conjunction error paradigm, a laboratory procedure known to elicit high levels of memory errors. For older adults, right parahippocampal gyrus showed significantly greater activity during false than during accurate retrieval. We observed no regions in which activity was greater during false than during accurate retrieval for young adults. Young adults, however, showed significantly greater activity than old adults during accurate retrieval in right hippocampus. By contrast, older adults demonstrated greater activity than young adults during accurate retrieval in right inferior and middle prefrontal cortex. These data are consistent with the notion that age-related memory conjunction errors arise from dysfunction of hippocampal system mechanisms, rather than impairments in frontally-mediated monitoring processes.en_US
dc.description.sponsorshipPsychologyen_US
dc.language.isoen_USen_US
dc.publisherMassachusetts Institute of Technology Pressen_US
dc.relation.isversionofdoi:10.1162/jocn.2009.21274en_US
dash.licenseLAA
dc.titleAged-Related Neural Changes During Memory Conjunction Errorsen_US
dc.typeJournal Articleen_US
dc.description.versionProofen_US
dc.relation.journalJournal of Cognitive Neuroscienceen_US
dash.depositing.authorSchacter, Daniel L.
dc.date.available2011-07-01T07:31:39Z
dc.identifier.doi10.1162/jocn.2009.21274*
dash.contributor.affiliatedKensinger, Elizabeth
dash.contributor.affiliatedSchacter, Daniel


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