Making Evolutionary Biology a Basic Science for Medicine
Nesse, Randolph M.
Bergstrom, Carl T.
Govindaraju, Diddahally R.
Omenn, Gil S.
Perlman, Robert L.
Thomas, Mark G.
Stearns, Stephen C.
Valle, DavidNote: Order does not necessarily reflect citation order of authors.
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CitationNesse, Randolph M., Carl T. Bergstrom, Peter T. Ellison, Jeffrey S. Flier, Peter Gluckman, Diddahally R. Govindaraju, Dietrich Niethammer, et al. Forthcoming. Making Evolutionary Biology a Basic Science for Medicine. Proceedings of the National Academy of Sciences 106.
AbstractNew applications of evolutionary biology in medicine are being discovered at an accelerating rate, but few physicians have sufficient educational background to utilize them fully. This article summarizes suggestions from several groups who have considered how evolutionary biology can be useful in medicine, what physicians should learn about it, and when and how they should learn it. Our general conclusion is that evolutionary biology is a crucial basic science for medicine. In addition to established evolutionary methods and topics, such as population genetics and pathogen evolution, the article also highlights questions about why natural selection leaves bodies vulnerable to disease. Knowledge about volution provides physicians with an integrative framework that links otherwise disparate bits of knowledge. It replaces the revalent view of bodies as machines with a biological view of bodies shaped by evolutionary processes.
Like other basic sciences, evolutionary biology needs to be taught both before and during medical school. Most introductory biology courses are insufficient to establish competency in evolutionary biology. Premedical students need evolution courses, possibly ones that emphasize medically relevant aspects. In medical school, evolutionary biology should be taught as one of the basic medical sciences. This will require a course that reviews basic principles and specific medical applications, followed by an integrated presentation of evolutionary aspects that apply to each disease and organ system. Evolutionary biology is not just another topic vying for inclusion in the curriculum; it is an essential foundation for a biological understanding of health and disease.
Citable link to this pagehttp://nrs.harvard.edu/urn-3:HUL.InstRepos:3685827
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