Developmentally-Inspired Shrink-Wrap Polymers for Mechanical Induction of Tissue Differentiation
Zarzar, Lauren D.
MetadataShow full item record
CitationHashmi, Basma, Lauren D. Zarzar, Tadanori Mammoto, Akiko Mammoto, Amanda Jiang, Joanna Aizenberg, and Donald E. Ingber. 2014. “Developmentally-Inspired Shrink-Wrap Polymers for Mechanical Induction of Tissue Differentiation.” Advanced Materials 26 (20) (February 18): 3253–3257. doi:10.1002/adma.201304995.
AbstractA biologically inspired thermoresponsive polymer has been developed that mechanically induces tooth differentiation in vitro and in vivo by promoting mesenchymal cell compaction as seen in each pore of the scaffold. This normally occurs during the physiological mesenchymal condensation response that triggers tooth formation in the embryo.
Citable link to this pagehttp://nrs.harvard.edu/urn-3:HUL.InstRepos:37255404
- FAS Scholarly Articles