Show simple item record

dc.contributor.authorPratt, Stephen Douglas
dc.contributor.authorKaczka, D
dc.contributor.authorHess, Philip E.
dc.date.accessioned2021-04-06T15:16:30Z
dc.date.issued2014
dc.identifierQuick submit: 2017-04-19T23:11:19-0400
dc.identifier.citationPratt, S.D., D.W. Kaczka, and P.E. Hess. 2014. “Observational Study of Changes in Epidural Pressure and Elastance During Epidural Blood Patch in Obstetric Patients.” International Journal of Obstetric Anesthesia 23 (2) (May): 144–150. doi:10.1016/j.ijoa.2014.01.003.en_US
dc.identifier.issn0959-289Xen_US
dc.identifier.urihttps://nrs.harvard.edu/URN-3:HUL.INSTREPOS:37367172*
dc.description.abstractBackground During an epidural blood patch, we inject blood until the patient describes mild back pressure, often leading to injection of more than 20 mL of blood. We undertook this study to measure the epidural pressures generated during an epidural blood patch and to identify the impact of volume on epidural elastance in obstetric patients. Methods This study was performed in postpartum patients who presented for an epidural blood patch with symptoms consistent with a postdural puncture headache. After identification of the epidural space using loss of resistance to air or saline, we measured static epidural pressure after each 5-mL injection of blood. Models were then fitted to the data and the epidural elastance and compliance calculated. Results Eighteen blood patches were performed on 17 patients. The mean final volume injected was 18.9 ± 7.8 mL [range 6 to 38 mL]. The mean final pressure generated was 13.1 ± 13.4 mmHg [range 2 to 56 mmHg]. A curvilinear relationship existed between volume injected and pressure, which was described by two models: (1) pressure = 0.0254 × (mL injected)2 + 0.0297 × mL, or (2) pressure = 0.0679 × mL1.742. The value for r2 was approximately 0.57 for both models. We found no correlation between the final pressure generated and the success of the EBP. Conclusions We found a curvilinear relationship between the volume of blood injected during an epidural blood patch and the pressure generated in the epidural space. However, there was a large variation in both the volume of blood and the epidural pressure generated. The clinical importance of this finding is not known. A larger study would be required to demonstrate whether pressure is a predictor of success.en_US
dc.language.isoen_USen_US
dc.publisherElsevier BVen_US
dc.relation.isversionofdoi:10.1016/j.ijoa.2014.01.003en_US
dc.relation.hasversionhttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC4536553/en_US
dash.licenseMETA_ONLY
dc.subjectEpidural blood patchen_US
dc.subjectPressureen_US
dc.subjectcomplianceen_US
dc.titleObservational Study of Changes in Epidural Pressure and Elastance During Epidural Blood Patch in Obstetric Patientsen_US
dc.typeJournal Articleen_US
dc.date.updated2017-04-20T03:11:07Z
dc.description.versionAccepted Manuscripten_US
dc.relation.journalInternational Journal of Obstetric Anesthesiaen_US
dash.depositing.authorPratt, Stephen Douglas
dc.date.available2014
dc.date.available2021-04-06T15:16:30Z
dc.identifier.doi10.1016/j.ijoa.2014.01.003*
dash.contributor.affiliatedKaczka, David
dash.contributor.affiliatedPratt, Stephen
dash.contributor.affiliatedHess, Philip


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record