Recommended implementation of arterial spin-labeled perfusion MRI for clinical applications: A consensus of the ISMRM perfusion study group and the European consortium for ASL in dementia
Detre, John A.
MacIntosh, Bradley J.
Parkes, Laura M.
van Osch, Matthias J. P.
Wang, Danny J. J.
Wong, Eric C.
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CitationAlsop, David, John A. Detre, Xavier Golay, Matthias Günther, Jeroen Hendrikse, Luis Hernandez-Garcia, Hanzhang Lu et al. "Recommended implementation of arterial spin-labeled perfusion MRI for clinical applications: A consensus of the ISMRM perfusion study group and the European consortium for ASL in dementia." Magnetic Resonance in Medicine 73, no. 1 (2014): 102-116. DOI: 10.1002/mrm.25607
AbstractThis article provides a summary statement of recommended implementations of arterial spin labeling (ASL) for clinical applications. It is a consensus of the ISMRM Perfusion Study Group and the European ‘ASL in Dementia’ consortium, both of whom met to reach this consensus in October 2012 in Amsterdam. Although ASL continues to undergo rapid technical development, we believe that current ASL methods are robust and ready to provide useful clinical information, and that a consensus statement on recommended implementations will help the clinical community to adopt a standardized approach. In this article we describe the major considerations and tradeoffs in implementing an ASL protocol, and provide specific recommendations for a standard approach. Our conclusions are that, as an optimal default implementation we recommend: pseudo-continuous labeling, background suppression, a segmented 3D readout without vascular crushing gradients, and calculation and presentation of both label/control difference images and cerebral blood flow in absolute units using a simplified model.
Citable link to this pagehttps://nrs.harvard.edu/URN-3:HUL.INSTREPOS:37371486
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