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dc.contributor.authorZhao, Wen
dc.contributor.authorLiu, Yuying
dc.contributor.authorCahill, Catherine
dc.contributor.authorYang, Wenlu
dc.contributor.authorRogers, Jack
dc.contributor.authorHuang, Xudong
dc.date.accessioned2022-06-29T16:22:53Z
dc.date.issued2009-05-20
dc.identifier.citationZhao, Wen, Yuying Liu, Catherine Cahill, Wenlu Yang, Jack Rogers, Xudong Huang. "The Role of T Cells in Osteoporosis, an Update." International Journal of Clinical and Experimental Pathology 2, no. 6 (2009): 544-552.
dc.identifier.issn1936-2625en_US
dc.identifier.urihttps://nrs.harvard.edu/URN-3:HUL.INSTREPOS:37372447*
dc.description.abstractEmerging evidence highlights the importance of the interplay between the bone and immune systems. That evidence bolsters a longstanding recognition that estrogen deficiency, infection, inflammation, and autoimmune disorders are associated with systemic and local bone loss. Yet, only recently has an understanding emerged that T lymphocytes and their products act as key regulators of osteoclast formation, life span, and activity. This review presents this understanding of the process of T lymphocytes and their products mediating osteoporosis and explores some of the most recent findings and hypotheses to explain their action in bone. A more complete appreciation of the interactions between immune and bone cells should lead to targeted therapeutic strategies for diseases that affect either or both systems.en_US
dc.language.isoen_USen_US
dc.publishere-Century Publishingen_US
dc.relation.isversionofhttp://www.ijcep.com/files/IJCEP904011.pdfen_US
dc.relation.hasversionhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC2713452/en_US
dash.licenseLAA
dc.subjectResearch Subject Categories::MEDICINE::Morphology, cell biology, pathology::Pathologyen_US
dc.titleThe Role of T Cells in Osteoporosis, an Updateen_US
dc.typeJournal Articleen_US
dc.description.versionVersion of Recorden_US
dc.relation.journalInternational Journal of Clinical and Experimental Pathologyen_US
dash.depositing.authorCahill, Catherine
dc.date.available2022-06-29T16:22:53Z
dash.source.volume2en_US
dash.source.page544-552en_US
dash.source.issue6en_US
dash.contributor.affiliatedRogers, Jack
dash.contributor.affiliatedHuang, Xudong
dash.contributor.affiliatedCahill, Catherine


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