dc.contributor.author | Suri, Pradeep | |
dc.contributor.author | Rainville, James | |
dc.contributor.author | Fitzmaurice, Garrett M. | |
dc.contributor.author | Katz, Jeffrey Neil | |
dc.contributor.author | Jamison, Robert Newlin | |
dc.contributor.author | Martha, Julia | |
dc.contributor.author | Hartigan, Carol | |
dc.contributor.author | Limke, Janet | |
dc.contributor.author | Jouve, Cristin | |
dc.contributor.author | Hunter, David J. | |
dc.date.accessioned | 2022-08-12T13:43:25Z | |
dc.date.issued | 2011-10-05 | |
dc.identifier.citation | Suri, Pradeep, James Rainville, Garrett M. Fitzmaurice, Jeffrey Neil Katz, Robert Newlin Jamison, Julia Martha, Carol Hartigan et al. "Acute low back pain is marked by variability: An internet-based pilot study." BMC Musculoskelet Disord 12, no. 1 (2011). DOI: 10.1186/1471-2474-12-220 | |
dc.identifier.issn | 1471-2474 | en_US |
dc.identifier.uri | https://nrs.harvard.edu/URN-3:HUL.INSTREPOS:37372994 | * |
dc.description.abstract | Background: Pain variability in acute LBP has received limited study. The objectives of this pilot study were to characterize fluctuations in pain during acute LBP, to determine whether self-reported 'flares' of pain represent discrete periods of increased pain intensity, and to examine whether the frequency of flares was associated with back-related disability outcomes. Methods: We conducted a cohort study of acute LBP patients utilizing frequent serial assessments and Internet-based data collection. Adults with acute LBP (lasting ≤3 months) completed questionnaires at the time of seeking care, and at both 3-day and 1-week intervals, for 6 weeks. Back pain was measured using a numerical pain rating scale (NPRS), and disability was measured using the Oswestry Disability Index (ODI). A pain flare was defined as 'a period of increased pain lasting at least 2 hours, when your pain intensity is distinctly worse than it has been recently'. We used mixed-effects linear regression to model longitudinal changes in pain intensity, and multivariate linear regression to model associations between flare frequency and disability outcomes. Results: 42 of 47 participants (89%) reported pain flares, and the average number of discrete flare periods per patient was 3.5 over 6 weeks of follow-up. More than half of flares were less than 4 hours in duration, and about 75% of flares were less than one day in duration. A model with a quadratic trend for time best characterized improvements in pain. Pain decreased rapidly during the first 14 days after seeking care, and leveled off after about 28 days. Patients who reported a pain flare experienced an almost 3-point greater current NPRS than those not reporting a flare (mean difference [SD] 2.70 [0.11]; p < 0.0001). Higher flare frequency was independently associated with a higher final ODI score (ß [SE} 0.28 (0.08); p = 0.002). Conclusions: Acute LBP is characterized by variability. Patients with acute LBP report multiple distinct flares of pain, which correspond to discrete increases in pain intensity. A higher flare frequency is associated with worse disability outcomes. | en_US |
dc.language.iso | en_US | en_US |
dc.publisher | Springer Science and Business Media LLC | en_US |
dc.relation.isversionof | doi:10.1186/1471-2474-12-220 | en_US |
dash.license | Pass Through | |
dc.subject | Orthopedics and Sports Medicine | en_US |
dc.subject | Rheumatology | en_US |
dc.title | Acute low back pain is marked by variability: An internet-based pilot study | en_US |
dc.type | Journal Article | en_US |
dc.description.version | Version of Record | en_US |
dc.relation.journal | BMC Musculoskelet Disord | en_US |
dash.depositing.author | Katz, Jeffrey Neil | |
dc.date.available | 2022-08-12T13:43:25Z | |
dc.identifier.doi | 10.1186/1471-2474-12-220 | * |
dash.source.volume | 12 | en_US |
dash.source.issue | 1 | en_US |
dash.contributor.affiliated | Fitzmaurice, Garrett | |
dash.contributor.affiliated | Jamison, Robert | |
dash.contributor.affiliated | Rainville, James | |
dash.contributor.affiliated | Hartigan, Carol | |
dash.contributor.affiliated | Hunter, David | |
dash.contributor.affiliated | Katz, Jeffrey | |