| dc.contributor.author | Wang, Ketai | |
| dc.contributor.author | Adelstein, Stanley | |
| dc.contributor.author | Kassis, Amin | |
| dc.date.accessioned | 2018-12-18T15:53:24Z | |
| dc.date.issued | 2008-01 | |
| dc.identifier.citation | Wang, Ketai, S. James Adelstein, and Amin I. Kassis. 2008. “DMSO Increases Radioiodination Yield of Radiopharmaceuticals.” Applied Radiation and Isotopes 66 (1): 50–59. https://doi.org/10.1016/j.apradiso.2007.07.026. | en_US |
| dc.identifier.issn | 0969-8043 | en_US |
| dc.identifier.uri | http://nrs.harvard.edu/urn-3:HUL.InstRepos:37933090 | * |
| dc.description.abstract | A high-yield radioiodination method for various types of molecules is described. The approach employs DMSO as precursor solvent, a reaction ratio of 2-5 precursor molecules per iodine atom, 5-10 mu g oxidant, and a 10-25 mu l reaction volume. The solution is vortexed at room temperature for 1-5 min and progress of the reaction is assessed by HPLC. Radioiodinated products are obtained in >= 95% yield and meet the requirements for radiotracer imaging, biodistribution studies, and molecular and cellular biology research. | en_US |
| dc.language.iso | en_US | en_US |
| dc.publisher | Elsevier BV | en_US |
| dash.license | LAA | |
| dc.title | DMSO Increases Radioiodination Yield of Radiopharmaceuticals | en_US |
| dc.type | Journal Article | en_US |
| dc.description.version | Accepted Manuscript | en_US |
| dc.relation.journal | Applied Radiation and Isotopes | en_US |
| dash.depositing.author | Adelstein, Stanley | |
| dc.date.available | 2018-12-18T15:53:24Z | |
| dash.workflow.comments | 1Science Serial ID 13920 | en_US |
| dc.identifier.doi | 10.1016/j.apradiso.2007.07.026 | |
| dc.source.journal | Applied Radiation and Isotopes | |
| dash.source.volume | 66;1 | |
| dash.source.page | 50-59 | |
| dash.contributor.affiliated | Kassis, Amin | |
| dash.contributor.affiliated | Adelstein, Stanley | |
