Expression of Candidate Pheromone Receptor Genes in Vomeronasal Neurons

View/ Open
23-4-467.pdf (1.019Mb)
Access Status
Full text of the requested work is not available in DASH at this time ("restricted access"). For more information on restricted deposits, see our FAQ.Published Version
https://doi.org/10.1093/chemse/23.4.467Metadata
Show full item recordCitation
Dulac, C., and R. Axel. 1998. “Expression of Candidate Pheromone Receptor Genes in Vomeronasal Neurons.” Chemical Senses 23 (4): 467–75. https://doi.org/10.1093/chemse/23.4.467.Abstract
In mammals, olfactory sensory perception is mediated by two anatomically and functionally distinct organs: the main olfactory epithelium (MOE) and the vomeronasal organ (VON). Pheromones activate the VNO and elicit a characteristic array of innate reproductive and social behaviors, along with dramatic neuroendocrine responses. Recent approaches have provided new insights into the molecular biology of sensory transduction in the VNO. Differential screening of cDNA libraries constructed from single sensory neurons from the rat VNO has led to the isolation of a family of genes which are likely to encode mammalian pheromone receptors. The isolation of these receptors from the VNO might permit the analysis of the molecular events which translate the bindings of pheromones into innate stereotypic behaviors and help to elucidate the logic of pheromone perception in mammals.Citable link to this page
http://nrs.harvard.edu/urn-3:HUL.InstRepos:37960816
Collections
- FAS Scholarly Articles [18179]
Contact administrator regarding this item (to report mistakes or request changes)