dc.contributor.author | Gunasekera, Nicole | |
dc.date.accessioned | 2019-06-24T12:19:15Z | |
dc.date.created | 2017-05 | |
dc.date.issued | 2019-03-27 | |
dc.date.submitted | 2017 | |
dc.identifier.citation | Gunasekera, Nicole. 2017. Vitiligo Screen Tool as an Innovative Method for Diagnosing and Studying Vitiligo. Doctoral dissertation, Harvard Medical School. | |
dc.identifier.uri | http://nrs.harvard.edu/urn-3:HUL.InstRepos:40621394 | * |
dc.description.abstract | Purpose: The pathology of vitiligo is not yet well understood. Most vitiligo research relies on asking a single survey question about ‘physician-diagnosed’ vitiligo to identify study participants. This self-reporting is not sufficient and limits accurate study of vitiligo. We developed and pilot-tested the VItiligo Screening TOol (VISTO) as a means to confirm vitiligo diagnoses. This study aimed to determine whether the VISTO is a sensitive and specific instrument for detection of vitiligo in an adult population.
Methods: The VISTO is a self-administered questionnaire consisting of 8 closed-ended questions that assess whether the respondent has been diagnosed with vitiligo by a healthcare provider. 140 completed questionnaires were analyzed, 43 cases and 97 controls from Brigham and Women’s Hospital outpatient dermatology clinic.
Results: The pictorial question had 100% sensitivity and 99% specificity for the diagnosis of vitiligo. Answering “yes” to being diagnosed with vitiligo by a dermatologist and choosing one photographic representation of vitiligo had 95.2% sensitivity and 100% specificity for diagnosis of vitiligo.
Conclusion: Based on these results, the VISTO is the first validated questionnaire that is highly sensitive and specific in identifying vitiligo among adult English speakers. | |
dc.description.sponsorship | Scholarly Project | |
dc.format.mimetype | application/pdf | |
dc.language.iso | en | |
dash.license | LAA | |
dc.subject | vitiligo | |
dc.subject | screening | |
dc.subject | dermatology | |
dc.title | Vitiligo Screen Tool as an Innovative Method for Diagnosing and Studying Vitiligo | |
dc.type | Thesis or Dissertation | |
dash.depositing.author | Gunasekera, Nicole | |
dc.date.available | 2019-06-24T12:19:15Z | |
thesis.degree.date | 2017 | |
thesis.degree.grantor | Harvard Medical School | |
thesis.degree.grantor | Harvard Medical School | |
thesis.degree.level | Doctoral | |
thesis.degree.level | Doctoral | |
thesis.degree.name | Doctor of Medicine | |
thesis.degree.name | Doctor of Medicine | |
dc.type.material | text | |
dash.identifier.vireo | | |
dash.title.page | 1 | |
dash.author.email | n.s.gunasekera@gmail.com | |