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dc.contributor.authorGunasekera, Nicole
dc.date.accessioned2019-06-24T12:19:15Z
dc.date.created2017-05
dc.date.issued2019-03-27
dc.date.submitted2017
dc.identifier.citationGunasekera, Nicole. 2017. Vitiligo Screen Tool as an Innovative Method for Diagnosing and Studying Vitiligo. Doctoral dissertation, Harvard Medical School.
dc.identifier.urihttp://nrs.harvard.edu/urn-3:HUL.InstRepos:40621394*
dc.description.abstractPurpose: The pathology of vitiligo is not yet well understood. Most vitiligo research relies on asking a single survey question about ‘physician-diagnosed’ vitiligo to identify study participants. This self-reporting is not sufficient and limits accurate study of vitiligo. We developed and pilot-tested the VItiligo Screening TOol (VISTO) as a means to confirm vitiligo diagnoses. This study aimed to determine whether the VISTO is a sensitive and specific instrument for detection of vitiligo in an adult population. Methods: The VISTO is a self-administered questionnaire consisting of 8 closed-ended questions that assess whether the respondent has been diagnosed with vitiligo by a healthcare provider. 140 completed questionnaires were analyzed, 43 cases and 97 controls from Brigham and Women’s Hospital outpatient dermatology clinic. Results: The pictorial question had 100% sensitivity and 99% specificity for the diagnosis of vitiligo. Answering “yes” to being diagnosed with vitiligo by a dermatologist and choosing one photographic representation of vitiligo had 95.2% sensitivity and 100% specificity for diagnosis of vitiligo. Conclusion: Based on these results, the VISTO is the first validated questionnaire that is highly sensitive and specific in identifying vitiligo among adult English speakers.
dc.description.sponsorshipScholarly Project
dc.format.mimetypeapplication/pdf
dc.language.isoen
dash.licenseLAA
dc.subjectvitiligo
dc.subjectscreening
dc.subjectdermatology
dc.titleVitiligo Screen Tool as an Innovative Method for Diagnosing and Studying Vitiligo
dc.typeThesis or Dissertation
dash.depositing.authorGunasekera, Nicole
dc.date.available2019-06-24T12:19:15Z
thesis.degree.date2017
thesis.degree.grantorHarvard Medical School
thesis.degree.grantorHarvard Medical School
thesis.degree.levelDoctoral
thesis.degree.levelDoctoral
thesis.degree.nameDoctor of Medicine
thesis.degree.nameDoctor of Medicine
dc.type.materialtext
dash.identifier.vireo
dash.title.page1
dash.author.emailn.s.gunasekera@gmail.com


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