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dc.contributor.authorTraulsen, Arne
dc.contributor.authorIwasa, Yoh
dc.contributor.authorNowak, Martin A.
dc.date.accessioned2010-05-10T13:37:09Z
dc.date.issued2007
dc.identifier.citationTraulsen, Arne, Yoh Iwasa, and Martin A. Nowak. 2007. The fastest evolutionary trajectory. Journal of Theoretical Biology 249(3): 617-623.en_US
dc.identifier.issn0022-5193en_US
dc.identifier.urihttp://nrs.harvard.edu/urn-3:HUL.InstRepos:4063693
dc.description.abstractGiven two mutants, A and B, separated by n mutational steps, what is the evolutionary trajectory which allows a homogeneous population of A to reach B in the shortest time? We show that the optimum evolutionary trajectory (fitness landscape) has the property that the relative fitness increase between any two consecutive steps is constant. Hence, the optimum fitness landscape between A and B is given by an exponential function. Our result is precise for small mutation rates and excluding back mutations. We discuss deviations for large mutation rates and including back mutations. For very large mutation rates, the optimum fitness landscape is flat and has a single peak at type B.en_US
dc.description.sponsorshipMathematicsen_US
dc.description.sponsorshipOrganismic and Evolutionary Biologyen_US
dc.language.isoen_USen_US
dc.publisherElsevieren_US
dc.relation.isversionofdoi:10.1016/j.jtbi.2007.08.012en_US
dash.licenseLAA
dc.subjectfinite populationsen_US
dc.subjectevolutionary dynamicsen_US
dc.titleThe Fastest Evolutionary Trajectoryen_US
dc.typeJournal Articleen_US
dc.description.versionAuthor's Originalen_US
dc.relation.journalJournal of Theoretical Biologyen_US
dash.depositing.authorNowak, Martin A.
dc.date.available2010-05-10T13:37:09Z
dc.identifier.doi10.1016/j.jtbi.2007.08.012*
dash.contributor.affiliatedNowak, Martin


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