Sugar-sweetened and artificially sweetened beverage consumption and risk of type 2 diabetes in men
7139 ajcn93501321.pdf (88.07Kb)
Access StatusFull text of the requested work is not available in DASH at this time ("restricted access"). For more information on restricted deposits, see our FAQ.
Koning, Lawrence de
Malik, Vasanti S.
Rimm, Eric Bruce::0ab2926c8242f35e5a982e3cf59f4987::600
Willett, Walter C.::94559ea206eef8a8844fc5b80654fa5b::600
Hu, Frank B.
MetadataShow full item record
CitationKoning, Lawrence de, Vasanti S Malik, Eric B Rimm, Walter C Willett, and Frank B Hu. 2011. “Sugar-Sweetened and Artificially Sweetened Beverage Consumption and Risk of Type 2 Diabetes in Men.” The American Journal of Clinical Nutrition 93 (6): 1321–27. https://doi.org/10.3945/ajcn.110.007922.
AbstractBackground: Sugar-sweetened beverages are risk factors for type 2 diabetes; however, the role of artificially sweetened beverages is unclear. Objective: The objective was to examine the associations of sugar- and artificially sweetened beverages with incident type 2 diabetes. Design: An analysis of healthy men (n = 40,389) from the Health Professionals Follow-Up Study, a prospective cohort study, was performed. Cumulatively averaged intakes of sugar-sweetened (sodas, fruit punches, lemonades, fruit drinks) and artificially sweetened (diet sodas, diet drinks) beverages from food-frequency questionnaires were tested for associations with type 2 diabetes by using Cox regression. Results: There were 2680 cases over 20 y of follow-up. After age adjustment, the hazard ratio (HR) for the comparison of the top with the bottom quartile of sugar-sweetened beverage intake was 1.25 (95% CI: 1.11, 1.39; P for trend < 0.01). After adjustment for confounders, including multivitamins, family history, high triglycerides at baseline, high blood pressure, diuretics, pre-enrollment weight change, dieting, total energy, and body mass index, the HR was 1.24 (95% CI: 1.09, 1.40; P for trend < 0.01). Intake of artificially sweetened beverages was significantly associated with type 2 diabetes in the age-adjusted analysis (HR: 1.91; 95% CI: 1.72, 2.11; P for trend < 0.01) but not in the multivariate-adjusted analysis (HR: 1.09; 95% CI: 0.98, 1.21; P for trend = 0.13). The replacement of one serving of sugar-sweetened beverage with 1 cup (approximate to 237 mL) of coffee was associated with a risk reduction of 17%. Conclusion: Sugar-sweetened beverage consumption is associated with a significantly elevated risk of type 2 diabetes, whereas the association between artificially sweetened beverages and type 2 diabetes was largely explained by health status, pre-enrollment weight change, dieting, and body mass index. Am J Clin Nutr 2011;93:1321-7.
Citable link to this pagehttp://nrs.harvard.edu/urn-3:HUL.InstRepos:41246924
- SPH Scholarly Articles