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dc.contributor.authorBernstein, A. M.
dc.contributor.authorDing, E. L.
dc.contributor.authorWillett, Walter C.::94559ea206eef8a8844fc5b80654fa5b::600
dc.contributor.authorRimm, Eric Bruce::0ab2926c8242f35e5a982e3cf59f4987::600
dc.date.accessioned2019-08-26T13:59:31Z
dc.date.issued2012
dc.identifier.citationBernstein, Adam M., Eric L. Ding, Walter C. Willett, and Eric B. Rimm. 2011. “A Meta-Analysis Shows That Docosahexaenoic Acid from Algal Oil Reduces Serum Triglycerides and Increases HDL-Cholesterol and LDL-Cholesterol in Persons without Coronary Heart Disease.” The Journal of Nutrition 142 (1): 99–104. https://doi.org/10.3945/jn.111.148973.
dc.identifier.issn0022-3166
dc.identifier.issn1541-6100
dc.identifier.urihttp://nrs.harvard.edu/urn-3:HUL.InstRepos:41246927*
dc.description.abstractCertain algae contain the (n-3) fatty acid DHA, yet the relation between algal oil supplementation and cardiovascular disease risk factors has not been systematically examined. Our objective was to examine the relation between algal oil supplementation and cardiovascular disease risk factors. We conducted a systematic review of randomized controlled trials published between 1996 and 2011 examining the relation between algal oil supplementation and cardiovascular disease risk factors and performed a meta-analysis of the association between algal oil DHA supplementation and changes in the concentrations of TG, LDL-cholesterol (LDL-C), and HDL-cholesterol (HDL-C). We identified 11 randomized controlled trials with 485 healthy participants that evaluated the relation between algal oil DHA supplementation and TG, LDL-C, and HDL-C. The median dose of algal DHA was 1.68 g/d. The pooled estimate for the change in TG concentration was -0.20 mmol/L (95% Cl: -0.27 to -0.14), 0.23 mmol/L (95% Cl: 0.16-0.30) for LDL-C, and 0.07 mmol/L 195% Cl: 0.05-0.101 for HDL-C. DHA supplementation from algal oil, a marine source of (n-3) fatty acids not extracted from fish, may reduce serum TG and increase HDL-C and LDL-C in persons without coronary heart disease. J. Nutr. 142: 99-104, 2012.
dc.language.isoen_US
dc.publisherOxford University Press
dash.licenseMETA_ONLY
dc.titleA Meta-Analysis Shows That Docosahexaenoic Acid from Algal Oil Reduces Serum Triglycerides and Increases HDL-Cholesterol and LDL-Cholesterol in Persons without Coronary Heart Disease
dc.typeJournal Article
dc.description.versionVersion of Record
dc.relation.journalThe Journal of Nutrition
dash.depositing.authorRimm, Eric Bruce::0ab2926c8242f35e5a982e3cf59f4987::600
dc.date.available2019-08-26T13:59:31Z
dash.workflow.comments1Science Serial ID 111942
dc.identifier.doi10.3945/jn.111.148973
dash.source.volume142;1
dash.source.page99-104


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