dc.contributor.author | Kivimäki, Mika | |
dc.contributor.author | Batty, G. David | |
dc.contributor.author | Hamer, Mark | |
dc.contributor.author | Nabi, Hermann | |
dc.contributor.author | Korhonen, Maarit | |
dc.contributor.author | Huupponen, Risto | |
dc.contributor.author | Pentti, Jaana | |
dc.contributor.author | Oksanen, Tuula | |
dc.contributor.author | Kawachi, Ichiro | |
dc.contributor.author | Virtanen, Marianna | |
dc.contributor.author | Westerlund, Hugo | |
dc.contributor.author | Vahtera, Jussi | |
dc.date.accessioned | 2019-08-29T04:59:24Z | |
dc.date.issued | 2013 | |
dc.identifier.citation | Kivimaki, M., G. D. Batty, M. Hamer, H. Nabi, M. Korhonen, R. Huupponen, J. Pentti, et al. 2013. “Influence of Retirement on Nonadherence to Medication for Hypertension and Diabetes.” Canadian Medical Association Journal 185 (17): E784–90. https://doi.org/10.1503/cmaj.122010. | |
dc.identifier.issn | 0820-3946 | |
dc.identifier.issn | 1488-2329 | |
dc.identifier.uri | http://nrs.harvard.edu/urn-3:HUL.InstRepos:41275573 | * |
dc.description.abstract | Background: The extent to which common life transitions influence medication adherence among patients remains unknown. We examined whether retirement is associated with a change in adherence to medication in patients with hypertension or type 2 diabetes.Methods: Participants in the Finnish Public Sector study were linked to national registers. We included data for the years 1994-2011. We identified and followed 3468 adult patients with hypertension and 412 adult patients with type 2 diabetes for medication adherence for the 3 years before their retirement and the 4 years after their retirement (mean follow-up 6.8 yr). Our primary outcome was proportion of patients with poor adherence to medication, which we defined as less than 40% of days covered by treatment. We determined these proportions before and after retirement using data from filled prescriptions.Results: The preretirement prevalence of poor adherence to medication was 6% in men and women with hypertension, 2% in men with diabetes and 4% in women with diabetes. Among men, retirement was associated with an increased risk of poor adherence to both antihypertensive agents (odds ratio [OR] 1.32, 95% confidence interval [CI] 1.03-1.68) and antidiabetic drugs (OR 2.40, 95% CI 1.37-4.20). Among women, an increased risk of poor adherence was seen only for antihypertensive agents (OR 1.25, 95% CI 1.07-1.46). Similar results were apparent for alternative definitions of poor adherence. Our results did not differ across strata of age, socioeconomic status or comorbidity.Interpretation: We found a decline in adherence to medication after retirement among men and women with hypertension and men with type 2 diabetes. If these findings can be confirmed, we need randomized controlled trials to determine whether interventions to reduce poor adherence after retirement could improve clinical outcomes of treatments for hypertension and diabetes. | |
dc.language.iso | en_US | |
dc.publisher | | |
dash.license | META_ONLY | |
dc.title | Influence of retirement on nonadherence to medication for hypertension and diabetes | |
dc.type | Journal Article | |
dc.description.version | Version of Record | |
dc.relation.journal | CMAJ - Canadian Medical Association Journal / Journal de l'Association médicale canadienne | |
dash.depositing.author | Kawachi, Ichiro::3b17e788dad605ac69e3dd457b6c41ac::600 | |
dc.date.available | 2019-08-29T04:59:24Z | |
dash.workflow.comments | 1Science Serial ID 24038 | |
dc.identifier.doi | 10.1503/cmaj.122010 | |
dash.source.volume | 185;17 | |
dash.source.page | E784 | |