Depressive Symptoms and Risk of Type 2 Diabetes in Women
MetadataShow full item record
CitationHannon, Tamara S, Dana L Rofey, SoJung Lee, and Silva A Arslanian. 2013. “Depressive Symptoms and Metabolic Markers of Risk for Type 2 Diabetes in Obese Adolescents.” Pediatric Diabetes 14 (7): 497–503. https://doi.org/10.1111/pedi.12035.
AbstractObjective - To explore the relationship between depressive symptoms and incidence of type 2 diabetes in women. Research design and methods - We conducted an analysis of 72,178 female nurses aged 45-72 years who did not have diagnosed diabetes and who answered the Medical Outcomes Study 36-Item Short-Form Health Status Survey (SF-36) at baseline in 1992. We calculated relative risks (RR) of type 2 diabetes for women with presence of depressive symptoms (i.e., Five-Item Mental Health Index [MHI-5] score >52). Results - During 4 years of follow-up (282,317 person-years), 973 incident cases of type 2 diabetes were documented. Age-adjusted RR of developing type 2 diabetes for women with presence of depressive symptoms was 1.55 (95% CI 1.27-1.90). Additional adjustment for BMI resulted in a RR of developing type 2 diabetes of 1.36 (1.11-1.67). The muitivariate RR of developing type 2 diabetes was 1.22 (1.00-1.50). After ex eluding women diagnosed with diabetes between 1992 and 1994, 472 incident cases of type 2 diabetes were documented for the follow-up period from 1994 to 1996 (148,889 person-years). The multivariate RR of developing type 2 diabetes for women with depressive symptoms was 1.29 (0.96-1.72). Conclusions - Our data suggest that depressive symptoms are associated with a modest increase in the risk of type 2 diabetes.
Citable link to this pagehttp://nrs.harvard.edu/urn-3:HUL.InstRepos:41275575
- SPH Scholarly Articles