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dc.contributor.authorSzulkin, Robert
dc.contributor.authorKarlsson, Robert
dc.contributor.authorWhitington, Thomas
dc.contributor.authorAly, Markus
dc.contributor.authorGronberg, Henrik
dc.contributor.authorEeles, Rosalind
dc.contributor.authorEaston, Douglas
dc.contributor.authorKote-Jarai, Zsofia
dc.contributor.authorOlama, Ali Amin Al
dc.contributor.authorBenlloch, Sara
dc.contributor.authorMuir, Kenneth
dc.contributor.authorGiles, Graham
dc.contributor.authorSouthey, Melissa
dc.contributor.authorFitzGerald, Liesel
dc.contributor.authorHenderson, Brian
dc.contributor.authorSchumacher, Fredrick
dc.contributor.authorHaiman, Christopher
dc.contributor.authorSipeky, Csilla
dc.contributor.authorTammela, Teuvo L. J.
dc.contributor.authorNordestgaard, Børge G.
dc.contributor.authorKey, Timothy
dc.contributor.authorTravis, Ruth
dc.contributor.authorNeal, David
dc.contributor.authorDonovan, Jenny
dc.contributor.authorHamdy, Freddie
dc.contributor.authorPharoah, Paul D. P.
dc.contributor.authorPashayan, Nora
dc.contributor.authorKhaw, Kay-Tee
dc.contributor.authorStanford, Janet
dc.contributor.authorThibodeau, Stephen
dc.contributor.authorMcDonnell, Shannon
dc.contributor.authorSchaid, Daniel
dc.contributor.authorMaier, Christiane
dc.contributor.authorVogel, Walther
dc.contributor.authorLuedeke, Manuel
dc.contributor.authorHerkommer, Kathleen
dc.contributor.authorKibel, Adam
dc.contributor.authorCybulski, Cezary
dc.contributor.authorLubiński, Jan
dc.contributor.authorKluźniak, Wojciech
dc.contributor.authorCannon-Albright, Lisa
dc.contributor.authorBrenner, Hermann
dc.contributor.authorHerrmann, Volker
dc.contributor.authorHolleczek, Bernd
dc.contributor.authorPark, Jong
dc.contributor.authorSellers, Thomas
dc.contributor.authorLim, Hui-Yi
dc.contributor.authorSlavov, Chavdar
dc.contributor.authorKaneva, Radka
dc.contributor.authorMitev, Vanio
dc.contributor.authorSpurdle, Amanda
dc.contributor.authorTeixeira, Manuel
dc.contributor.authorPaulo, Paula
dc.contributor.authorMaia, Sofia
dc.contributor.authorPandha, Hardev
dc.contributor.authorMichael, Agnieszka
dc.contributor.authorKierzek, Andrzej
dc.contributor.authorBatra, Jyotsna
dc.contributor.authorClements, Judith
dc.contributor.authorAlbanes, Demetrius
dc.contributor.authorAndriole, Gerald
dc.contributor.authorBerndt, Sonja
dc.contributor.authorChanock, Stephen
dc.contributor.authorGapstur, Susan
dc.contributor.authorGiovannucci, Edward
dc.contributor.authorHunter, David
dc.contributor.authorKraft, Peter
dc.contributor.authorLe Marchand, Loic
dc.contributor.authorMa, Jing
dc.contributor.authorMondul, Alison
dc.contributor.authorPenney, Kathryn
dc.contributor.authorStampfer, Meir
dc.contributor.authorStevens, Victoria
dc.contributor.authorWeinstein, Stephanie
dc.contributor.authorTrichopoulou, Antonia
dc.contributor.authorBueno-de-Mesquita, Bas
dc.contributor.authorTjonneland, Anne
dc.contributor.authorCox, David
dc.contributor.authorMaehle, Lovise
dc.contributor.authorSchleutker, Johanna
dc.contributor.authorLindström, Sara
dc.contributor.authorWiklund, Fredrik
dc.date.accessioned2019-09-05T15:17:05Z
dc.date.issued2015
dc.identifier.citationSzulkin, R., R. Karlsson, T. Whitington, M. Aly, H. Gronberg, R. A. Eeles, D. F. Easton, et al. 2015. “Genome-Wide Association Study of Prostate Cancer-Specific Survival.” Cancer Epidemiology Biomarkers & Prevention 24 (11): 1796–1800. https://doi.org/10.1158/1055-9965.epi-15-0543.
dc.identifier.issn1055-9965
dc.identifier.issn1538-7755
dc.identifier.urihttp://nrs.harvard.edu/urn-3:HUL.InstRepos:41292457*
dc.description.abstractBackground: Unnecessary intervention and overtreatment of indolent disease are common challenges in clinical management of prostate cancer. Improved tools to distinguish lethal from indolent disease are critical. Methods: We performed a genome-wide survival analysis of cause-specific death in 24,023 prostate cancer patients (3,513 disease-specific deaths) from the PRACTICAL and BPC3 consortia. Top findings were assessed for replication in a Norwegian cohort (CONOR). Results: We observed no significant association between genetic variants and prostate cancer survival. Conclusions: Common genetic variants with large impact on prostate cancer survival were not observed in this study.Impact: Future studies should be designed for identification of rare variants with large effect sizes or common variants with small effect sizes.
dc.language.isoen_US
dc.publisherAmerican Association for Cancer Research
dash.licenseOAP
dc.titleGenome-wide association study of prostate cancer-specific survival
dc.typeJournal Article
dc.description.versionAccepted Manuscript
dc.relation.journalCancer Epidemiology, Biomarkers & Prevention
dash.depositing.authorStampfer, Meir
dc.date.available2019-09-05T15:17:05Z
dash.workflow.comments1Science Serial ID 26488
dc.identifier.doi10.1158/1055-9965.EPI-15-0543
dash.source.volume24;11
dash.source.page1796
dash.contributor.affiliatedStampfer, Meir


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