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dc.contributor.authorNock, Matthew K.
dc.contributor.authorHwang, Irving
dc.contributor.authorSampson, Nancy A.
dc.date.accessioned2010-05-25T14:22:34Z
dc.date.issued2009
dc.identifier.citationNock, Matthew K., Irving Hwang, Nancy A. Sampson. 2009. Mental disorders, comorbidity, and suicidal behavior: results from the national comorbidity survey replication. Molecular Psychiatry (March 31), doi:10.1038/mp.2009.29.en_US
dc.identifier.issn1359-4184en_US
dc.identifier.urihttp://nrs.harvard.edu/urn-3:HUL.InstRepos:4133811
dc.description.abstractMental disorders are among the strongest predictors of suicide attempts. However, little is known about which disorders are uniquely associated with suicidal behavior due to high levels of psychiatric comorbidity. We examined the unique associations between individual disorders and subsequent suicidal behavior (suicide ideation, plans, and attempts) using data from the National Comorbidity Survey Replication, a nationally representative household survey of 9,282 US adults. Results revealed that approximately 80% of suicide attempters in the US have a temporally prior mental disorder. Anxiety, mood, impulse-control, and substance disorders all significantly predict subsequent suicide attempts in bivariate analyses (odds ratios=2.7-6.7); however, these associations decrease substantially in multivariate analyses controlling for comorbidity (odds ratios=1.5-2.3) but remain statistically significant in most cases. Disaggregation of the observed effects reveals that depression predicts suicide ideation, but not suicide plans or attempts among those with ideation. Instead, disorders characterized by severe anxiety/agitation (e.g., PTSD) and poor impulse-control (e.g., conduct disorder, substance disorders) predict which suicide ideators go on to make a plan or attempt. These results advance understanding of the unique associations between mental disorders and different forms of suicidal behavior. Future research must further delineate the mechanisms through which people come to think about suicide and progress from suicidal thoughts to attempts.en_US
dc.description.sponsorshipPsychologyen_US
dc.language.isoen_USen_US
dc.publisherNature Publishing Groupen_US
dc.relation.isversionofdoi:10.1038/mp.2009.29en_US
dash.licenseOAP
dc.subjectepidemiologyen_US
dc.subjectmental disordersen_US
dc.subjectpsychopathologyen_US
dc.subjectcomorbidityen_US
dc.subjectNCS-Ren_US
dc.subjectsuicideen_US
dc.subjectsuicidal ideationen_US
dc.subjectsuicide attempten_US
dc.titleMental Disorders, Comorbidity, and Suicidal Behavior: Results from the National Comorbidity Survey Replicationen_US
dc.typeJournal Articleen_US
dc.description.versionAccepted Manuscripten_US
dc.relation.journalMolecular Psychiatryen_US
dash.depositing.authorNock, Matthew K.
dc.date.available2010-05-25T14:22:34Z
dc.identifier.doi10.1038/mp.2009.29*
dash.contributor.affiliatedHwang, Irving
dash.contributor.affiliatedSampson, Nancy
dash.contributor.affiliatedNock, Matthew


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