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dc.contributor.authorHäcker, Udo
dc.contributor.authorNybakken, Kent
dc.contributor.authorPerrimon, Norbert
dc.date.accessioned2019-09-21T09:03:25Z
dc.date.issued2005
dc.identifier.citationHäcker, Udo, Kent Nybakken, and Norbert Perrimon. 2005. “Heparan Sulphate Proteoglycans: The Sweet Side of Development.” Nature Reviews Molecular Cell Biology 6 (7): 530–41. https://doi.org/10.1038/nrm1681.
dc.identifier.issn1471-0072
dc.identifier.issn1471-0080
dc.identifier.urihttp://nrs.harvard.edu/urn-3:HUL.InstRepos:41384498*
dc.description.abstractPattern formation during development is controlled to a great extent by a small number of conserved signal transduction pathways that are activated by extracellular ligands such as Hedgehog, Wingless or Decapentaplegic. Genetic experiments have identified heparan sulphate proteoglycans (HSPGs) as important regulators of the tissue distribution of these extracellular signalling molecules. Several recent reports provide important new insights into the mechanisms by which HSPGs function during development.
dc.language.isoen_US
dc.publisherNature Research (part of Springer Nature)
dash.licenseMETA_ONLY
dc.titleHeparan sulphate proteoglycans: the sweet side of development
dc.typeJournal Article
dc.description.versionVersion of Record
dc.relation.journalNature Reviews - Molecular Cell Biology
dash.depositing.authorPerrimon, Norbert::4e34fce71a186b488b1846b199007bfb::600
dc.date.available2019-09-21T09:03:25Z
dash.workflow.comments1Science Serial ID 68628
dc.identifier.doi10.1038/nrm1681
dash.source.volume6;7
dash.source.page530-541


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