Nutritional Predictors of Acute Respiratory Infections Among Children Born to HIV-Infected Women in Tanzania
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CitationMwiru, R., D. Spiegelman, E. Hertzmark, C. Duggan, G. Msamanga, S. Aboud, and W. Fawzi. 2013. “Nutritional Predictors of Acute Respiratory Infections Among Children Born to HIV-Infected Women in Tanzania.” Journal of Tropical Pediatrics 59 (3): 203–8. https://doi.org/10.1093/tropej/fmt004.
AbstractWe prospectively determined the association between undernutrition and incidence of acute respiratory infections (ARIs) among 711 children born to HIV-infected women. Overall, underweight was associated with a 58% increased risk of ARI. Similarly, wasting (54%), very low birth weight (88%) and child HIV infection (62%) were significantly associated with increased risk of ARI during the first 2 years. Breastfeeding was associated with 52% reduction in risk of ARI only during the first 12 months of life. Among HIV-exposed, but uninfected, children, underweight, wasting and stunting were associated with 73%, 61% and 33% increased risk of ARI, respectively. Very low birthweight and advanced maternal disease stage were also associated with increased risk of ARI. Similar results were observed among HIV-infected children, except for stunting and very low birth weight. Prevention of child undernutrition could have major impact in reducing child ARI morbidity in settings of high HIV prevalence.
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