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dc.contributor.authorForrester, J. E.
dc.contributor.authorSpiegelman, D.
dc.contributor.authorWoods, M.
dc.contributor.authorKnox, T. A.
dc.contributor.authorFauntleroy, J. M.
dc.contributor.authorGorbach, S. L.
dc.date.accessioned2019-09-21T16:11:44Z
dc.date.issued2001
dc.identifier.citationForrester, JE, D Spiegelman, M Woods, TA Knox, JM Fauntleroy, and SL Gorbach. 2001. “Weight and Body Composition in a Cohort of HIV-Positive Men and Women.” Public Health Nutrition 4 (3): 743–47. https://doi.org/10.1079/phn200099.
dc.identifier.issn1368-9800
dc.identifier.issn1475-2727
dc.identifier.urihttp://nrs.harvard.edu/urn-3:HUL.InstRepos:41384731*
dc.description.abstractObjective. At issue is whether weight loss in HIV infection is a cachectic process, characterised by loss of lean body mass with conservation of fat, or a process of starvation. We present data on body composition from 516 persons at different stages of HIV infection as determined by CD4 counts. Design: Cross-sectional analyses of body composition in relation to CD4 count. Setting: The baseline data from a prospective cohort study of outcomes in HIV/AIDS in relation to nutritional status in Boston, Massachusetts, USA.Subjects: The first 516 subjects with HIV/AIDS to enrol in the study. Results: Differences in weight in relation to CD4 counts were present only at CD4 counts of 600 or less (slope below CD4 = 600: 1.9 kg per 100 CD4 cells, P < 0.0001). On average, 68% of the difference in weight over CD4 counts was fat (slope: 1.3 kg fat per 100 CD4 cells, P < 0.0001). Conclusions: This cross-sectional analysis suggests that weight loss consists principally of fat loss in those persons with adequate fat stores. This observation will need to be confirmed in longitudinal analyses.
dc.language.isoen_US
dc.publisherCambridge University Press
dash.licenseLAA
dc.titleWeight and body composition in a cohort of HIV-positive men and women
dc.typeJournal Article
dc.description.versionVersion of Record
dc.relation.journalPublic Health Nutrition
dash.depositing.authorSpiegelman, Donna::37eeac21962b33e4e46e7aedde542849::600
dc.date.available2019-09-21T16:11:44Z
dash.workflow.comments1Science Serial ID 84516
dc.identifier.doi10.1079/PHN200099
dash.source.volume4;3
dash.source.page743


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