dc.contributor.author | Schumacher, Fredrick | |
dc.contributor.author | Schmit, Stephanie | |
dc.contributor.author | Jiao, Shuo | |
dc.contributor.author | Edlund, Christopher | |
dc.contributor.author | Wang, Hansong | |
dc.contributor.author | Zhang, Ben | |
dc.contributor.author | Hsu, Li | |
dc.contributor.author | Huang, Shu-Chen | |
dc.contributor.author | Fischer, Christopher | |
dc.contributor.author | Harju, John | |
dc.contributor.author | Idos, Gregory | |
dc.contributor.author | Lejbkowicz, Flavio | |
dc.contributor.author | Manion, Frank | |
dc.contributor.author | McDonnell, Kevin | |
dc.contributor.author | McNeil, Caroline | |
dc.contributor.author | Melas, Marilena | |
dc.contributor.author | Rennert, Hedy | |
dc.contributor.author | Shi, Wei | |
dc.contributor.author | Thomas, Duncan | |
dc.contributor.author | Van Den Berg, David J. | |
dc.contributor.author | Hutter, Carolyn | |
dc.contributor.author | Aragaki, Aaron | |
dc.contributor.author | Butterbach, Katja | |
dc.contributor.author | Caan, Bette | |
dc.contributor.author | Carlson, Christopher | |
dc.contributor.author | Chanock, Stephen | |
dc.contributor.author | Curtis, Keith | |
dc.contributor.author | Fuchs, Charles | |
dc.contributor.author | Gala, Manish | |
dc.contributor.author | Giovannucci, Edward | |
dc.contributor.author | Gogarten, Stephanie | |
dc.contributor.author | Hayes, Richard | |
dc.contributor.author | Henderson, Brian | |
dc.contributor.author | Hunter, David | |
dc.contributor.author | Jackson, Rebecca | |
dc.contributor.author | Kolonel, Laurence | |
dc.contributor.author | Kooperberg, Charles | |
dc.contributor.author | Sébastien Küry | |
dc.contributor.author | LaCroix, Andrea | |
dc.contributor.author | Laurie, Cathy | |
dc.contributor.author | Laurie, Cecelia | |
dc.contributor.author | Lemire, Mathieu | |
dc.contributor.author | Levine, David | |
dc.contributor.author | Ma, Jing | |
dc.contributor.author | Makar, Karen | |
dc.contributor.author | Qu, Conghui | |
dc.contributor.author | Taverna, Darin | |
dc.contributor.author | Ulrich, Cornelia | |
dc.contributor.author | Wu, Kana | |
dc.contributor.author | Kono, Suminori | |
dc.contributor.author | West, Dee | |
dc.contributor.author | Berndt, Sonja | |
dc.contributor.author | Stéphane Bezieau | |
dc.contributor.author | Brenner, Hermann | |
dc.contributor.author | Campbell, Peter | |
dc.contributor.author | Chan, Andrew | |
dc.contributor.author | Chang-Claude, Jenny | |
dc.contributor.author | Coetzee, Gerhard | |
dc.contributor.author | Conti, David | |
dc.contributor.author | Duggan, David | |
dc.contributor.author | Figueiredo, Jane | |
dc.contributor.author | Fortini, Barbara | |
dc.contributor.author | Gallinger, Steven | |
dc.contributor.author | Gauderman, W. James | |
dc.contributor.author | Giles, Graham | |
dc.contributor.author | Green, Roger | |
dc.contributor.author | Haile, Robert | |
dc.contributor.author | Harrison, Tabitha | |
dc.contributor.author | Hoffmeister, Michael | |
dc.contributor.author | Hopper, John | |
dc.contributor.author | Hudson, Thomas | |
dc.contributor.author | Jacobs, Eric | |
dc.contributor.author | Iwasaki, Motoki | |
dc.contributor.author | Jee, Sun Ha | |
dc.contributor.author | Jenkins, Mark | |
dc.contributor.author | Jia, Wei-Hua | |
dc.contributor.author | Joshi, Amit | |
dc.contributor.author | Li, Li | |
dc.contributor.author | Lindor, Noralene | |
dc.contributor.author | Matsuo, Keitaro | |
dc.contributor.author | Moreno, Victor | |
dc.contributor.author | Mukherjee, Bhramar | |
dc.contributor.author | Newcomb, Polly | |
dc.contributor.author | Potter, John | |
dc.contributor.author | Raskin, Leon | |
dc.contributor.author | Rennert, Gad | |
dc.contributor.author | Rosse, Stephanie | |
dc.contributor.author | Severi, Gianluca | |
dc.contributor.author | Schoen, Robert | |
dc.contributor.author | Seminara, Daniela | |
dc.contributor.author | Shu, Xiao-Ou | |
dc.contributor.author | Slattery, Martha | |
dc.contributor.author | Tsugane, Shoichiro | |
dc.contributor.author | White, Emily | |
dc.contributor.author | Xiang, Yong-Bing | |
dc.contributor.author | Zanke, Brent | |
dc.contributor.author | Zheng, Wei | |
dc.contributor.author | Le Marchand, Loic | |
dc.contributor.author | Casey, Graham | |
dc.contributor.author | Gruber, Stephen | |
dc.date.accessioned | 2019-09-23T15:34:06Z | |
dc.date.issued | 2015 | |
dc.identifier.citation | Schumacher, Fredrick R., Stephanie L. Schmit, Shuo Jiao, Christopher K. Edlund, Hansong Wang, Ben Zhang, Li Hsu, et al. 2015. “Genome-Wide Association Study of Colorectal Cancer Identifies Six New Susceptibility Loci.” Nature Communications 6 (1). https://doi.org/10.1038/ncomms8138. | |
dc.identifier.issn | 2041-1723 | |
dc.identifier.uri | http://nrs.harvard.edu/urn-3:HUL.InstRepos:41392051 | * |
dc.description.abstract | Genetic susceptibility to colorectal cancer is caused by rare pathogenic mutations and common genetic variants that contribute to familial risk. Here we report the results of a two-stage association study with 18,299 cases of colorectal cancer and 19,656 controls, with follow-up of the most statistically significant genetic loci in 4,725 cases and 9,969 controls from two Asian consortia. We describe six new susceptibility loci reaching a genome-wide threshold of P<5.0E - 08. These findings provide additional insight into the underlying biological mechanisms of colorectal cancer and demonstrate the scientific value of large consortia-based genetic epidemiology studies. | |
dc.language.iso | en_US | |
dc.publisher | Nature Research (part of Springer Nature) | |
dash.license | OAP | |
dc.title | Genome-wide association study of colorectal cancer identifies six new susceptibility loci | |
dc.type | Journal Article | |
dc.description.version | Accepted Manuscript | |
dc.relation.journal | Nature Communications | |
dash.depositing.author | Giovannucci, Edward L.::fd8dcb59a5a5859f2a85fabae12a60cf::600 | |
dc.date.available | 2019-09-23T15:34:06Z | |
dash.workflow.comments | 1Science Serial ID 73040 | |
dc.identifier.doi | 10.1038/ncomms8138 | |
dash.source.volume | 6 | |
dash.source.page | 7138 | |