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dc.contributor.authorMeyer, Mara S.
dc.contributor.authorJoshipura, Kaumudi
dc.contributor.authorGiovannucci, Edward
dc.contributor.authorMichaud, Dominique S.
dc.date.accessioned2019-09-23T15:34:16Z
dc.date.issued2008
dc.identifier.citationMeyer, Mara S., Kaumudi Joshipura, Edward Giovannucci, and Dominique S. Michaud. 2008. “A Review of the Relationship between Tooth Loss, Periodontal Disease, and Cancer.” Cancer Causes & Control 19 (9): 895–907. https://doi.org/10.1007/s10552-008-9163-4.
dc.identifier.issn0957-5243
dc.identifier.issn1573-7225
dc.identifier.urihttp://nrs.harvard.edu/urn-3:HUL.InstRepos:41392069*
dc.description.abstractRecent studies have investigated the association between periodontal disease, tooth loss, and several systemic diseases including cancer, cardiovascular disease, and preterm birth. Periodontal disease, a chronic inflammatory condition, is highly prevalent in adult populations around the world, and may be preventable. Estimates of prevalence vary between races and geographic regions, with a marked increase in the occurrence of periodontal disease with advancing age. Worldwide estimates for the prevalence of severe periodontal disease generally range from 10 to 15%. The relationship between oral health and cancer has been examined for a number of specific cancer sites. Several studies have reported associations between periodontal disease or tooth loss and risk of oral, upper gastrointestinal, lung, and pancreatic cancer in different populations. In a number of studies, these associations persisted after adjustment for major risk factors, including cigarette smoking and socioeconomic status. This review provides a summary of these findings, discusses possible biological mechanisms involved, and raises methodological issues related to studying these relationships.
dc.language.isoen_US
dc.publisherSpringer (part of Springer Nature)
dash.licenseLAA
dc.titleA Review of the Relationship between Tooth Loss, Periodontal Disease, and Cancer
dc.typeJournal Article
dc.description.versionAccepted Manuscript
dc.relation.journalCancer Causes and Control
dash.depositing.authorGiovannucci, Edward L.::fd8dcb59a5a5859f2a85fabae12a60cf::600
dc.date.available2019-09-23T15:34:16Z
dash.workflow.comments1Science Serial ID 24199
dc.identifier.doi10.1007/s10552-008-9163-4
dash.source.volume19;9
dash.source.page895


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