dc.contributor.author | Hume, Maxwell A. | |
dc.contributor.author | Barrera, Luis A. | |
dc.contributor.author | Gisselbrecht, Stephen S. | |
dc.contributor.author | Bulyk, Martha L. | |
dc.date.accessioned | 2019-10-05T03:28:51Z | |
dc.date.issued | 2015 | |
dc.identifier.citation | Hume, Maxwell A., Luis A. Barrera, Stephen S. Gisselbrecht, and Martha L. Bulyk. 2014. “UniPROBE, Update 2015: New Tools and Content for the Online Database of Protein-Binding Microarray Data on protein–DNA Interactions.” Nucleic Acids Research 43 (D1): D117–22. https://doi.org/10.1093/nar/gku1045. | |
dc.identifier.issn | 0305-1048 | |
dc.identifier.issn | 1362-4962 | |
dc.identifier.uri | http://nrs.harvard.edu/urn-3:HUL.InstRepos:41483027 | * |
dc.description.abstract | The Universal PBM Resource for Oligonucleotide Binding Evaluation (UniPROBE) serves as a convenient source of information on published data generated using universal protein-binding microarray (PBM) technology, which provides in vitro data about the relative DNA-binding preferences of transcription factors for all possible sequence variants of a length k ('k-mers'). The database displays important information about the proteins and displays their DNA-binding specificity data in terms of k-mers, position weight matrices and graphical sequence logos. This update to the database documents the growth of UniPROBE since the last update 4 years ago, and introduces a variety of new features and tools, including a new streamlined pipeline that facilitates data deposition by universal PBM data generators in the research community, a tool that generates putative nonbinding (i.e. negative control) DNA sequences for one or more proteins and novel motifs obtained by analyzing the PBM data using the BEEML-PBM algorithm for motif inference. The UniPROBE database is available at http://uniprobe.org. | |
dc.language.iso | en_US | |
dc.publisher | Oxford University Press | |
dash.license | LAA | |
dc.title | UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein–DNA interactions | |
dc.type | Journal Article | |
dc.description.version | Version of Record | |
dc.relation.journal | Nucleic Acids Research | |
dash.depositing.author | Bulyk, Martha L.::45ae122f2e8ae5175ec5bb093ae1d488::600 | |
dc.date.available | 2019-10-05T03:28:51Z | |
dash.workflow.comments | 1Science Serial ID 74856 | |
dc.identifier.doi | 10.1093/nar/gku1045 | |
dash.source.volume | 43;Database issue | |