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dc.contributor.authorLin, Yi-Chia
dc.contributor.authorYao, Norman Y.
dc.contributor.authorBroedersz, Chase P.
dc.contributor.authorHerrmann, Harald
dc.contributor.authorMacKintosh, Fred C.
dc.contributor.authorWeitz, David A.
dc.date.accessioned2019-10-09T13:56:40Z
dc.date.issued2010
dc.identifier.citationLin, Yi-Chia, Norman Y. Yao, Chase P. Broedersz, Harald Herrmann, Fred C. MacKintosh, and David A. Weitz. 2010. “Origins of Elasticity in Intermediate Filament Networks.” Physical Review Letters104 (5): 058101. https://doi.org/10.1103/PhysRevLett.104.058101.
dc.identifier.issn0031-9007
dc.identifier.issn1079-7114
dc.identifier.issn1092-0145
dc.identifier.urihttp://nrs.harvard.edu/urn-3:HUL.InstRepos:41511267*
dc.description.abstractIntermediate filaments are common structural elements found in abundance in all metazoan cells, where they form networks that contribute to the elasticity. Here, we report measurements of the linear and nonlinear viscoelasticity of networks of two distinct intermediate filaments, vimentin and neurofilaments. Both exhibit predominantly elastic behavior with strong nonlinear strain stiffening. We demonstrate that divalent ions behave as effective cross-linkers for both networks, and that the elasticity of these networks is consistent with the theory for that of semiflexible polymers.
dc.language.isoen_US
dc.publisherAmerican Physical Society
dash.licenseLAA
dc.titleOrigins of Elasticity in Intermediate Filament Networks
dc.typeJournal Article
dc.description.versionVersion of Record
dc.relation.journalPhysical Review Letters
dash.depositing.authorWeitz, David A.::4c144b06be6d094b21dbe2dd12dbef76::600
dc.date.available2019-10-09T13:56:40Z
dash.workflow.comments1Science Serial ID 78572
dc.identifier.doi10.1103/PhysRevLett.104.058101
dash.source.volume104;5


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