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dc.contributor.authorZeng, Ling-Li
dc.contributor.authorWang, Danhong
dc.contributor.authorFox, Michael
dc.contributor.authorSabuncu, Mert
dc.contributor.authorHu, Dewen
dc.contributor.authorGe, Manling
dc.contributor.authorBuckner, Randy
dc.contributor.authorLiu, Hesheng
dc.date.accessioned2019-10-17T05:19:12Z
dc.date.issued2014
dc.identifier.citationZeng, L.-L., D. Wang, M. D. Fox, M. Sabuncu, D. Hu, M. Ge, R. L. Buckner, and H. Liu. 2014. “Neurobiological Basis of Head Motion in Brain Imaging.” Proceedings of the National Academy of Sciences 111 (16). Proceedings of the National Academy of Sciences: 6058–62. doi:10.1073/pnas.1317424111.
dc.identifier.issn0027-8424
dc.identifier.issn0744-2831
dc.identifier.issn1091-6490
dc.identifier.urihttp://nrs.harvard.edu/urn-3:HUL.InstRepos:41555774*
dc.description.abstractIndividual differences in brain metrics, especially connectivity measured with functional MRI, can correlate with differences in motion during data collection. The assumption has been that motion causes artifactual differences in brain connectivity that must and can be corrected. Here we propose that differences in brain connectivity can also represent a neurobiological trait that predisposes to differences in motion. We support this possibility with an analysis of intra- versus intersubject differences in connectivity comparing high- to low-motion subgroups. Intersubject analysis identified a correlate of head motion consisting of reduced distant functional connectivity primarily in the default network in individuals with high head motion. Similar connectivity differences were not found in analysis of intrasubject data. Instead, this correlate of head motion was a stable property in individuals across time. These findings suggest that motion-associated differences in brain connectivity cannot fully be attributed to motion artifacts but rather also reflect individual variability in functional organization.
dc.language.isoen_US
dc.publisherNational Academy of Sciences
dash.licenseLAA
dc.titleNeurobiological basis of head motion in brain imaging
dc.typeJournal Article
dc.description.versionVersion of Record
dc.relation.journalProceedings of the National Academy of Sciences of the United States of America
dash.depositing.authorBuckner, Randy::232ac1d8d8611564f621928b5fabddc4::600
dc.date.available2019-10-17T05:19:12Z
dash.workflow.comments1Science Serial ID 91190
dc.identifier.doi10.1073/pnas.1317424111
dash.source.volume111;16
dash.source.page6058


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