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dc.contributor.authorSackton, Timothy
dc.date.accessioned2020-04-07T11:04:50Z
dc.date.issued2019-02
dc.identifier.citationSackton, Timothy B. "Comparative Genomics and Transcriptomics of Host-pathogen Interactions in Insects: Evolutionary Insights and Future Directions." Current Opinion in Insect Science 31 (2018): 106-113.en_US
dc.identifier.issn2214-5745en_US
dc.identifier.urihttp://nrs.harvard.edu/urn-3:HUL.InstRepos:42656562*
dc.description.abstractClassical evolutionary studies of protein-coding genes have established that genes in the canonical immune system are often among the most rapidly evolving within and between species. As more genomes and transcriptomes across insects are sequenced, it is becoming clear that duplications and losses of immune genes are also a likely consequence of host-pathogen interactions. Furthermore, particular species respond to diverse pathogenic challenges with a wide range of challenge-specific responses that are still poorly understood. Transcriptional studies, using RNA-seq to characterize the infection-regulated transcriptome of diverse insects, are crucial for additional progress in understanding the ecology and evolution of the full complexity of the host response.en_US
dc.description.sponsorshipOrganismic and Evolutionary Biologyen_US
dc.language.isoen_USen_US
dc.publisherElsevier BVen_US
dash.licenseOAP
dc.subjectInsect Scienceen_US
dc.subjectEcology, Evolution, Behavior and Systematicsen_US
dc.titleComparative genomics and transcriptomics of host–pathogen interactions in insects: evolutionary insights and future directionsen_US
dc.typeJournal Articleen_US
dc.description.versionAccepted Manuscripten_US
dc.relation.journalCurrent Opinion in Insect Scienceen_US
dash.depositing.authorSackton, Timothy
dc.date.available2020-04-07T11:04:50Z
dash.affiliation.otherFaculty of Arts & Sciencesen_US
dc.identifier.doi10.1016/j.cois.2018.12.007
dc.source.journalCurrent Opinion in Insect Science
dash.source.page106-113
dash.contributor.affiliatedSackton, Timothy


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