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dc.contributor.authorLai, Shengjie
dc.contributor.authorRuktanonchai, Nick W
dc.contributor.authorZhou, Liangcai
dc.contributor.authorProsper, Olivia
dc.contributor.authorLuo, Wei
dc.contributor.authorFloyd, Jessica R
dc.contributor.authorWesolowski, Amy
dc.contributor.authorSantillana, Mauricio
dc.contributor.authorZhang, Chi
dc.contributor.authorDu, Xiangjun
dc.contributor.authorYu, Hongjie
dc.contributor.authorTatem, Andrew J
dc.date.accessioned2020-04-24T13:36:43Z
dc.identifier.citationLai, Shengjie, Nick W. Ruktanonchai, Liangcai Zhou, Olivia Prosper, Wei Luo, et al. Effect of non-pharmaceutical interventions to contain COVID-19 in China (2020)en_US
dc.identifier.urihttp://nrs.harvard.edu/urn-3:HUL.InstRepos:42661263*
dc.description.abstractOn March 11, 2020, the World Health Organization declared COVID-19 a pandemic1. The outbreak containment strategies in China based on non-pharmaceutical interventions (NPIs) appear to be effective2, but quantitative research is still needed to assess the efficacy of NPIs and their timings.3 Using epidemiological and anonymised human movement data4,5, here we develop a modelling framework that uses daily travel networks to simulate different outbreak and intervention scenarios across China. We estimated that there were a total of 114,325 COVID-19 cases (interquartile range 76,776 - 164,576) in mainland China as of February 29, 2020. Without NPIs, the COVID-19 cases would likely have shown a 67-fold increase (interquartile range 44 - 94), with the effectiveness of different interventions varying. The early detection and isolation of cases was estimated to have prevented more infections than travel restrictions and contact reductions, but combined NPIs achieved the strongest and most rapid effect. The lifting of travel restrictions since February 17, 2020 does not appear to lead to an increase in cases across China if the social distancing interventions can be maintained, even at a limited level of 25% reduction on average through late April. Our findings contribute to an improved understanding of NPIs on COVID-19 and to inform response efforts across the World.en_US
dc.language.isoen_USen_US
dc.publisherNature Researchen_US
dc.relationNatureen_US
dash.licenseLAA
dc.titleEffect of non-pharmaceutical interventions to contain COVID-19 in Chinaen_US
dc.typeJournal Articleen_US
dc.description.versionAccepted Manuscripten_US
dash.depositing.authorSantillana, Mauricio
dash.waiver2020-04-20
dc.date.available2020-04-24T13:36:43Z
dash.affiliation.otherHarvard Medical Schoolen_US
dash.waiver.reasonNature Research publishing have noted that one or more authors of the manuscript are from an institution (Harvard) that has an open access policy in place, which is incompatible with the business model for this journal.en_US
dash.contributor.affiliatedLuo, Wei
dash.contributor.affiliatedSantillana, Mauricio


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