Browsing Harvard Medical School by Author "Uchida, Naoshige"
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The dorsomedial striatum encodes net expected return, critical for energizing performance vigor
Wang, Alice Y.; Miura, Keiji; Uchida, Naoshige (2013)Decision making requires an actor to not only steer behavior towards specific goals, but also determine the optimal vigor of performance. Current research and models have largely focused on the former problem of how actions ... -
A Novel Excitatory Paraventricular Nucleus to AgRP Neuron Circuit that Drives Hunger
Krashes, Michael J.; Shah, Bhavik P.; Madara, Joseph C.; Olson, David P.; Strochlic, David E.; Garfield, Alastair S.; Vong, Linh; Pei, Hongjuan; Watabe-Uchida, Mitsuko; Uchida, Naoshige; Liberles, Stephen D.; Lowel, Bradford B. (2014)Summary Hunger is a hard-wired motivational state essential for survival. Agouti-related peptide (AgRP)-expressing neurons in the arcuate nucleus (ARC) at the base of the hypothalamus are crucial to its control. They are ...