Browsing Harvard Medical School by Title
Now showing items 1145-1164 of 18424
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Assessment of cleaning to control lead dust in homes of children with moderate lead poisoning: treatment of lead-exposed children trial
(National Institute of Environmental Health Sciences, 2002)In this article we describe the assessment and control of lead dust exposure in the Treatment of Lead-exposed Children (TLC) Trial, a clinical trial of the effects of oral chelation on developmental end points in urban ... -
An assessment of community health workers’ ability to screen for cardiovascular disease risk with a simple, non-invasive risk assessment instrument in Bangladesh, Guatemala, Mexico, and South Africa: an observational study
(2016)Summary Background: Cardiovascular disease contributes substantially to the non-communicable disease (NCD) burden in low-income and middle-income countries, which also often have substantial health personnel shortages. In ... -
Assessment of Definitions of Sustained Disease Progression in Relapsing-Remitting Multiple Sclerosis
(Hindawi Publishing Corporation, 2013)Sustained progression on the expanded disability status scale (EDSS) is a common outcome measure of disease progression in clinical studies of MS. Unfortunately, this outcome may not accurately measure long-term and ... -
Assessment of Echocardiography and Biomarkers for the Extended Prediction of Cardiotoxicity in Patients Treated With Anthracyclines, Taxanes, and Trastuzumab
(Ovid Technologies (Wolters Kluwer Health), 2012)Background: Because cancer patients survive longer, the impact of cardiotoxicity associated with the use of cancer treatments escalates. The present study investigates whether early alterations of myocardial strain and ... -
Assessment of Fractionated Exhaled Nitric Oxide as a Biomarker for the Treatment of Eosinophilic Esophagitis
(OceanSide Publications, Inc., 2012)Diagnosis of eosinophilic esophagitis (EoE) and determination of response to therapy is based on histological assessment of the esophagus, which requires upper endoscopy. In children, in whom a dietary approach is commonly ... -
Assessment of functional development in normal infant brain using arterial spin labeled perfusion MRI
(Elsevier BV, 2008-02)Arterial spin labeled (ASL) perfusion MRI provides a noninvasive approach for longitudinal imaging of regional brain function in infants. In the present study, continuous ASL (CASL) perfusion MRI was carried out in normally ... -
Assessment of Gene Order Computing Methods for Alzheimer's Disease
(Springer Science and Business Media LLC, 2013)Background Computational genomics of Alzheimer disease (AD), the most common form of senile dementia, is a nascent field in AD research. The field includes AD gene clustering by computing gene order which generates higher ... -
Assessment of PaO2/FiO2 for stratification of patients with moderate and severe acute respiratory distress syndrome
(BMJ Publishing Group, 2015)Objectives: A recent update of the definition of acute respiratory distress syndrome (ARDS) proposed an empirical classification based on ratio of arterial partial pressure of oxygen to fraction of inspired oxygen (PaO2/FiO2) ... -
Assessment of Perioperative Morbidity for Radical Cystectomy in Elderly Patients
(2015-06-08)OBJECTIVE: To assess the perioperative morbidity and impact of comorbidities in elderl patients undergoing radical cystectomy (RC) for bladder cancer. PATIENTS AND METHODS: A retrospective study of 52 patients greater ... -
Assessment of pharmacogenomic agreement
(F1000Research, 2016)In 2013 we published an analysis demonstrating that drug response data and gene-drug associations reported in two independent large-scale pharmacogenomic screens, Genomics of Drug Sensitivity in Cancer (GDSC) and Cancer ... -
Assessment of Priority Non-Communicable Diseases and Injuries (NCDI) Interventions and Human Resourcing at Selected Health Facilities in Four Regions of Ethiopia
(2021-06-25)Background and Rationale: Non-communicable diseases and injuries (NCDIs) are now major causes of mortality and morbidity globally. The Ethiopian NCDI Commission launched in 2018, estimated the burden of NCDIs as the causes ... -
Assessment of regional pulmonary blood flow using 68Ga-DOTA PET
(Springer Berlin Heidelberg, 2017)Background: In vivo determination of regional pulmonary blood flow (PBF) is a valuable tool for the evaluation of many lung diseases. In this study, the use of 68Ga-DOTA PET for the in vivo quantitative determination of ... -
Assessment of Response to Lithium Maintenance Treatment in Bipolar Disorder: A Consortium on Lithium Genetics (ConLiGen) Report
(Public Library of Science, 2013)Objective: The assessment of response to lithium maintenance treatment in bipolar disorder (BD) is complicated by variable length of treatment, unpredictable clinical course, and often inconsistent compliance. Prospective ... -
An Assessment of the Cost-Utility of Therapy for Psoriasis
(Dove Medical Press, 2006)Objective: Recently a number of new therapies have been introduced to treat psoriasis, but concerns have been expressed about their high cost. The purpose of this study was to determine whether most psoriasis treatments ... -
Assessment of the face validity of two pain scales in Kenya: a validation study using cognitive interviewing
(BioMed Central, 2012)Background: Patients in sub-Saharan Africa commonly experience pain, which often is un-assessed and undertreated. One hindrance to routine pain assessment in these settings is the lack of a single-item pain rating scale ... -
Assessment of the Frequency-Domain Multi-Distance Method to Evaluate the Brain Optical Properties: Monte Carlo Simulations from Neonate to Adult
(Optical Society of America, 2011)The near infrared spectroscopy (NIRS) frequency-domain multi-distance (FD-MD) method allows for the estimation of optical properties in biological tissue using the phase and intensity of radiofrequency modulated light at ... -
Assessment of the patient, health system, and population effects of Xpert MTB/RIF and alternative diagnostics for tuberculosis in Tanzania: an integrated modelling approach
(Elsevier, 2014)Background: Several promising new diagnostic methods and algorithms for tuberculosis have been endorsed by WHO. National tuberculosis programmes now face the decision on which methods to implement and where to place them ... -
Assessment of the prognostic and predictive utility of the Breast Cancer Index (BCI): an NCIC CTG MA.14 study
(BioMed Central, 2016)Background: Biomarkers that can be used to accurately assess the residual risk of disease recurrence in women with hormone receptor–positive breast cancer are clinically valuable. We evaluated the prognostic value of the ...