Now showing items 15009-15028 of 18424

    • Risk of ESRD and All Cause Mortality in Type 2 Diabetes According to Circulating Levels of FGF-23 and TNFR1 

      Lee, Jung Eun; Gohda, Tomohito; Walker, William H.; Skupien, Jan; Smiles, Adam M.; Holak, Rita R.; Jeong, Jackson; McDonnell, Kevin P.; Krolewski, Andrzej Stefan; Niewczas, Monika Anna (Public Library of Science, 2013)
      Introduction: Recent studies demonstrated that circulating fibroblast growth factor (FGF)-23 was associated with risk of end stage renal disease (ESRD) and mortality. This study aims to examine whether the predictive effect ...
    • Risk of Heart Failure in Breast Cancer Patients After Anthracycline and Trastuzumab Treatment: A Retrospective Cohort Study 

      Bowles, Erin J. Aiello; Wellman, Robert; Feigelson, Heather Spencer; Onitilo, Adedayo A.; Freedman, Andrew N.; Delate, Thomas; Allen, Larry A.; Nekhlyudov, Larissa; Goddard, Katrina A. B.; Davis, Robert L.; Habel, Laurel A.; Yood, Marianne Ulcickas; Mccarty, Catherine; Magid, David J.; Wagner, Edward H. (Oxford University Press, 2012)
      Background: Clinical trials demonstrated that women treated for breast cancer with anthracycline or trastuzumab are at increased risk for heart failure and/or cardiomyopathy (HF/CM), but the generalizability of these ...
    • Risk of Ischemic Cerebrovascular and Coronary Events in Adult Users of Anticonvulsant Medications in Routine Care Settings 

      Patorno, Elisabetta; Glynn, Robert J.; Hernandez‐Diaz, Sonia; Avorn, Jerry; Wahl, Peter M.; Bohn, Rhonda L.; Mines, Daniel; Liu, Jun; Schneeweiss, Sebastian (Blackwell Publishing Ltd, 2013)
      Background: Older‐generation anticonvulsants that highly induce cytochrome P450 enzyme system activity produce metabolic abnormalities that may increase cardiovascular risk. The objective of this study was to evaluate the ...
    • Risk of Ovarian Cancer and the NF- B Pathway: Genetic Association with IL1A and TNFSF10 

      Charbonneau, B.; Block, M. S.; Bamlet, W. R.; Vierkant, R. A.; Kalli, K. R.; Fogarty, Z.; Rider, D. N.; Sellers, T. A.; Tworoger, Shelley Slate; Poole, Elizabeth M.; Risch, H. A.; Salvesen, H. B.; Kiemeney, L. A.; Baglietto, L.; Giles, G. G.; Severi, G.; Trabert, B.; Wentzensen, N.; Chenevix-Trench, G.; Whittemore, A. S.; Sieh, W.; Chang-Claude, J.; Bandera, E. V.; Orlow, I.; Terry, Kathryn Lynne; Goodman, M. T.; Thompson, P. J.; Cook, L. S.; Rossing, M. A.; Ness, R. B.; Narod, S. A.; Kupryjanczyk, J.; Lu, K.; Butzow, R.; Dork, T.; Pejovic, T.; Campbell, I.; Le, N. D.; Bunker, C. H.; Bogdanova, N.; Runnebaum, I. B.; Eccles, D.; Paul, J.; Wu, A. H.; Gayther, S. A.; Hogdall, E.; Heitz, F.; Kaye, S. B.; Karlan, B. Y.; Anton-Culver, H.; Gronwald, J.; Hogdall, C. K.; Lambrechts, D.; Fasching, P. A.; Menon, U.; Schildkraut, J.; Pearce, C. L.; Levine, D. A.; Kjaer, S. K.; Cramer, Daniel William; Flanagan, J. M.; Phelan, C. M.; Brown, Robert; Massuger, L. F. A. G.; Song, H.; Doherty, J. A.; Krakstad, C.; Liang, D.; Odunsi, K.; Berchuck, A.; Jensen, A.; Lubinski, J.; Nevanlinna, H.; Bean, Y. T.; Lurie, G.; Ziogas, A.; Walsh, C.; Despierre, E.; Brinton, L.; Hein, A.; Rudolph, A.; Dansonka-Mieszkowska, A.; Olson, S. H.; Harter, P.; Tyrer, J.; Vitonis, A. F.; Brooks-Wilson, A.; Aben, K. K.; Pike, M. C.; Ramus, S. J.; Wik, E.; Cybulski, C.; Lin, J.; Sucheston, L.; Edwards, Robert R; McGuire, V.; Lester, J.; du Bois, A.; Lundvall, L.; Wang-Gohrke, S.; Szafron, L. M.; Lambrechts, S.; Yang, H.; Beckmann, M. W.; Pelttari, L. M.; Van Altena, A. M.; van den Berg, D.; Halle, M. K.; Gentry-Maharaj, A.; Schwaab, I.; Chandran, U.; Menkiszak, J.; Ekici, A. B.; Wilkens, L. R.; Leminen, A.; Modugno, F.; Friel, G.; Rothstein, J. H.; Vergote, I.; Garcia-Closas, M.; Hildebrandt, M. A. T.; Sobiczewski, P.; Kelemen, L. E.; Pharoah, P. D. P.; Moysich, K.; Knutson, K. L.; Cunningham, J. M.; Fridley, B. L.; Goode, E. L. (American Association for Cancer Research (AACR), 2013)
      A missense single-nucleotide polymorphism (SNP) in the immune modulatory gene IL1A has been associated with ovarian cancer risk (rs17561). Although the exact mechanism through which this SNP alters risk of ovarian cancer ...
    • Risk of Pneumonia in Obstructive Lung Disease: A Real-Life Study Comparing Extra-Fine and Fine-Particle Inhaled Corticosteroids 

      Sonnappa, Samatha; Martin, Richard J.; Israel, Elliot; Postma, Dirkje S.; van Aalderen, Wim; Burden, Annie; Usmani, Omar S.; Price, David B. (Public Library of Science (PLoS), 2017-06-15)
      Background Regular use of inhaled corticosteroids (ICS) in patients with obstructive lung diseases has been associated with a higher risk of pneumonia, particularly in COPD. The risk of pneumonia has not been previously ...
    • Risk of venous thromboembolism after total hip and knee replacement in older adults with comorbidity and co-occurring comorbidities in the Nationwide Inpatient Sample (2003-2006) 

      Kapoor, Alok; Labonte, Alan J; Winter, Michael R; Segal, Jodi B; Silliman, Rebecca A; Katz, Jeffrey Neil; Losina, Elena; Berlowitz, Dan (Springer Science and Business Media LLC, 2010-09-17)
      Background: Venous thromboembolism is a common, fatal, and costly injury which complicates major surgery in older adults. The American College of Chest Physicians recommends high potency prophylaxis regimens for individuals ...
    • The Risk of Virologic Failure Decreases with Duration of HIV Suppression, at Greater than 50% Adherence to Antiretroviral Therapy 

      Rosenblum, Michael; Deeks, Steven G.; van der Laan, Mark; Bangsberg, David Roy (Public Library of Science, 2009)
      Background: We hypothesized that the percent adherence to antiretroviral therapy necessary to maintain HIV suppression would decrease with longer duration of viral suppression. Methodology: Eligible participants were ...
    • Risk Prediction for Breast, Endometrial, and Ovarian Cancer in White Women Aged 50 y or Older: Derivation and Validation from Population-Based Cohort Studies 

      Pfeiffer, Ruth M.; Park, Yikyung; Kreimer, Aimée R.; Lacey, James V.; Pee, David; Greenlee, Robert T.; Buys, Saundra S.; Hollenbeck, Albert; Rosner, Bernard; Gail, Mitchell H.; Hartge, Patricia (Public Library of Science, 2013)
      Background: Breast, endometrial, and ovarian cancers share some hormonal and epidemiologic risk factors. While several models predict absolute risk of breast cancer, there are few models for ovarian cancer in the general ...
    • Risk Prediction in Aortic Valve Replacement: Incremental Value of the Preoperative Echocardiogram 

      Tan, Timothy C.; Flynn, Aidan W.; Chen‐Tournoux, Annabel; Rudski, Lawrence G.; Mehrotra, Praveen; Nunes, Maria C.; Rincon, Luis M.; Shahian, David M.; Picard, Michael H.; Afilalo, Jonathan (John Wiley and Sons Inc., 2015)
      Background: Risk prediction is a critical step in patient selection for aortic valve replacement (AVR), yet existing risk scores incorporate very few echocardiographic parameters. We sought to evaluate the incremental ...
    • Risk Profiles and Antithrombotic Treatment of Patients Newly Diagnosed with Atrial Fibrillation at Risk of Stroke: Perspectives from the International, Observational, Prospective GARFIELD Registry 

      Kakkar, Ajay K.; Mueller, Iris; Bassand, Jean-Pierre; Fitzmaurice, David A.; Goldhaber, Samuel Zachary; Goto, Shinya; Haas, Sylvia; Hacke, Werner; Lip, Gregory Y. H.; Mantovani, Lorenzo G.; Turpie, Alexander G. G.; van Eickels, Martin; Misselwitz, Frank; Rushton-Smith, Sophie; Kayani, Gloria; Wilkinson, Peter; Verheugt, Freek W. A. (Public Library of Science, 2013)
      Background: Limited data are available on the characteristics, clinical management, and outcomes of patients with atrial fibrillation at risk of stroke, from a worldwide perspective. The aim of this study was to describe ...
    • Risk Stratification by Regadenoson Stress Magnetic Resonance Imaging in Patients With Known or Suspected Coronary Artery Disease 

      Abbasi, Siddique Akbar; Heydari, Bobak; Shah, Ravi Vikram; Murthy, Venkatesh N.; Zhang, Ying-Yi; Blankstein, Ron; Steigner, Michael L.; Jerosch-Herold, Michael; Kwong, Raymond Yan-Kit (Elsevier BV, 2014)
      The aim of this study was to investigate the association between major adverse cardiovascular events (MACEs) and inducible ischemia on regadenoson cardiac magnetic resonance (CMR) myocardial perfusion imaging (MPI) performed ...
    • Risk Taking in Hospitalized Patients with Acute and Severe Traumatic Brain Injury 

      Fecteau, Shirley; Levasseur-Moreau, Jean; García-Molina, Alberto; Kumru, Hatiche; Vergara, Raúl Pelayo; Bernabeu, Monste; Roig, Teresa; Pascual-Leone, Alvaro; Tormos, José Maria (Public Library of Science, 2013)
      Rehabilitation can improve cognitive deficits observed in patients with traumatic brain injury (TBI). However, despite rehabilitation, the ability of making a choice often remains impaired. Risk taking is a daily activity ...
    • Risk-Adjusted Survival after Coronary Artery Bypass Grafting: Implications for Quality Improvement 

      Efird, Jimmy T.; O’Neal, Wesley T.; Davies, Stephen W.; O’Neal, Jason B.; Kindell, Linda C.; Anderson, Curtis A.; Chitwood, W. Randolph; Ferguson, T. Bruce; Kypson, Alan P. (MDPI, 2014)
      Mortality represents an important outcome measure following coronary artery bypass grafting. Shorter survival times may reflect poor surgical quality and an increased number of costly postoperative complications. Quality ...
    • Risk-communication Capability for Public Health Emergencies Varies by Community Diversity 

      Savoia, Elena; Stoto, Michael A.; Biddinger, Paul D.; Campbell, Paul H.; Viswanath, Kasisomayajula; Koh, Howard K (BioMed Central, 2008)
      Background: Public health emergencies heighten several challenges in risk-communication: providing trustworthy sources of information, reaching marginalized populations, and minimizing fear and public confusion. In ...
    • Risks and outcomes associated with disorganized/controlling patterns of attachment at age three years in the National Institute of Child Health & Human Development Study of Early Child Care and Youth Development 

      O'connor, Erin; Bureau, Jean-Francois; Mccartney, Kathleen; Lyons-Ruth, Karlen (Wiley, 2011)
      Disorganized/controlling attachment in preschool has been found to be associated with maternal and child maladjustment, making it of keen interest in the study of psychopathology. Additional work is needed, however, to ...
    • Risks Associated With Lentiviral Vector Exposures and Prevention Strategies 

      Schlimgen, Ryan; Howard, John; Wooley, Dawn; Thompson, Maureen; Baden, Lindsey R.; Yang, Otto O.; Christiani, David C.; Mostoslavsky, Gustavo; Diamond, David V.; Duane, Elizabeth Gilman; Byers, Karen; Winters, Thomas; Gelfand, Jeffrey A.; Fujimoto, Gary; Hudson, T. Warner; Vyas, Jatin M. (Lippincott Williams & Wilkins, 2016)
      Lentiviral vectors (LVVs) are powerful genetic tools that are being used with greater frequency in biomedical laboratories and clinical trials. Adverse events reported from initial clinical studies provide a basis for risk ...
    • Risks of Complications by Attending Physicians After Performing Nighttime Procedures 

      Rothschild, Jeffrey; Keohane, Carol A.; Rogers, Selwyn; Gardner, Roxane; Lipsitz, Stuart; Salzberg, Claudia A.; Yu, Tony; Yoon, Catherine S.; Williams, Deborah H.; Wien, Matt F.; Czeisler, Charles; Bates, David; Landrigan, Christopher (American Medical Association (AMA), 2009-10-14)
      Context: Few data exist on the relationships between experienced physicians' work hours and sleep, and patient safety. Objective: To determine if sleep opportunities for attending surgeons and obstetricians/gynecologists ...
    • Risk‐Treatment Paradox in the Selection of Transradial Access for Percutaneous Coronary Intervention 

      Wimmer, Neil J.; Resnic, Frederic S.; Mauri, Laura; Matheny, Michael E.; Piemonte, Thomas C.; Pomerantsev, Eugene; Ho, Kalon K. L.; Robbins, Susan L.; Waldman, Howard M.; Yeh, Robert W. (Blackwell Publishing Ltd, 2013)
      Background: Access site complications contribute to morbidity and mortality during percutaneous coronary intervention (PCI). Transradial arterial access significantly lowers the risk of access site complications compared ...
    • RMRP Is a Non-Coding RNA Essential for Early Murine Development 

      Rosenbluh, Joseph; Nijhawan, Deepak; Chen, Zhao; Wong, Kwok-Kin; Masutomi, Kenkichi; Hahn, William C.; Bellusci, Saverio (Public Library of Science, 2011)
      RMRP is a non-coding RNA that is ubiquitously expressed in both humans and mice. RMRP mutations that lead to decreased RMRP levels are found in the pleiotropic syndrome Cartilage Hair Hypoplasia. To assess the effects of ...
    • RNA - ligand interactions:(I) magnesium binding sites in yeast tRNA Phe 

      Holbrook, Stephen R.; Sussman, Joel L.; Warrant, R. Wade; Church, George; Kim, Sung-Hou (Oxford University Press (OUP), 1977)
      X-ray crystallagraphic studies studies indicate that there are at least four site-specifically bound hydrated Mg2+ ions, [Mg(H2O)n]2+, in yeast tRNAPhe. The size and the octahedral coordination geometry, rather than the ...