Browsing Harvard Medical School by Title
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Can enriching emotional intelligence improve medical students’ proactivity and adaptability during OB/GYN clerkships?
(IJME, 2015)Objectives: The purpose of this pilot study was to examine our hypothesis that enriching workplace emotional intelligence through resident coaches could improve third-year medical students’ adaptability and proactivity on ... -
Can Focused Trauma Education Initiatives Reduce Mortality or Improve Resource Utilization in a Low-Resource Setting?
(Springer Nature, 2014)BACKGROUND: Over 90% of injury deaths occur in low-income countries. Evaluating the impact of focused trauma courses in these settings is challenging. We hypothesized that implementation of a focused trauma education ... -
Can Managed Health Care Help Manage Health Care-Associated Infections?
(National Center for Infectious Diseases, 2001)Managed-care organizations have a unique opportunity, still largely unrealized, to collaborate with health-care providers and epidemiologists to prevent health care-associated infections. Several attributes make these ... -
Can Modeling of HIV Treatment Processes Improve Outcomes? Capitalizing on an Operations Research Approach to the Global Pandemic
(BioMed Central, 2008)Background: Mathematical modeling has been applied to a range of policy-level decisions on resource allocation for HIV care and treatment. We describe the application of classic operations research (OR) techniques to address ... -
Can osteoarthritis be treated with light?
(BioMed Central, 2013)Osteoarthritis is becoming more problematic as the population ages. Recent reports suggest that the benefit of anti-inflammatory drugs is unimpressive and the incidence of side effects is worrying. Low-level laser (light) ... -
Can purchasing information be used to predict adherence to cardiovascular medications? An analysis of linked retail pharmacy and insurance claims data
(BMJ Publishing Group, 2016)Objective: The use of retail purchasing data may improve adherence prediction over approaches using healthcare insurance claims alone. Design: Retrospective. Setting and participants A cohort of patients who received ... -
Canadian Open Genetics Repository (COGR): a unified clinical genomics database as a community resource for standardising and sharing genetic interpretations
(BMJ Publishing Group, 2015)Background: The Canadian Open Genetics Repository is a collaborative effort for the collection, storage, sharing and robust analysis of variants reported by medical diagnostics laboratories across Canada. As clinical ... -
Cancer and liver cirrhosis: implications on prognosis and management
(BMJ Publishing Group, 2016)Liver cirrhosis, the end-stage of every chronic liver disease, is not only the major risk factor for the development of hepatocellular carcinoma but also a limiting factor for anticancer therapy of liver and non-hepatic ... -
Cancer aneuploidies are shaped primarily by effects on tumour fitness
(Springer Science and Business Media LLC, 2023-06-28)Aneuploidies—whole-chromosome or whole-arm imbalances—are the most prevalent alteration in cancer genomes1,2. However, it is still debated whether their prevalence is due to selection or because they are readily generated ... -
Cancer cell profiling by barcoding allows multiplexed protein analysis in fine needle aspirates
(American Association for the Advancement of Science, 2014) -
Cancer Cell-Derived Clusterin Modulates the Phosphatidylinositol 3'-Kinase-Akt Pathway through Attenuation of Insulin-Like Growth Factor 1 during Serum Deprivation
(American Society for Microbiology, 2008)Cancer cells in their respective microenvironments must endure various growth-constraining stresses. Under these conditions, the cancer cell-derived factors are thought to modulate the signaling pathways between cell growth ... -
Cancer in first-degree relatives of people with celiac disease
(Wolters Kluwer Health, 2016)Abstract Background: Celiac disease (CD) has been linked to cancer, especially lymphoproliferative malignancy (LPM). Earlier research has shown that first-degree relatives (FDRs) to individuals with CD are at increased ... -
Cancer Incidence Among Those Initiating Insulin Therapy With Glargine Versus Human NPH Insulin
(American Diabetes Association, 2013)OBJECTIVE To add to the evidence on comparative long-term effects of insulin analog glargine versus human NPH insulin on the risk for cancer. RESEARCH DESIGN AND METHODS We identified cohorts of initiators of glargine and ... -
Cancer Incidence following Expansion of HIV Treatment in Botswana
(Public Library of Science, 2015)Background: The expansion of combination antiretroviral treatment (ART) in southern Africa has dramatically reduced mortality due to AIDS-related infections, but the impact of ART on cancer incidence in the region is ... -
Cancer Mortality in Chinese Chrysotile Asbestos Miners: Exposure-Response Relationships
(Public Library of Science, 2013)Objective: This study was conducted to assess the relationship of mortality from lung cancer and other selected causes to asbestos exposure levels. Methods: A cohort of 1539 male workers from a chrysotile mine in China was ... -
Cancer Nanomedicine: From Targeted Delivery to Combination Therapy
(2015)The advent of nanomedicine marks an unparalleled opportunity to advance the treatment of a variety of diseases, including cancer. The unique properties of nanoparticles, such as large surface-to volume ratio, small size, ... -
Cancer nanotechnology: The impact of passive and active targeting in the era of modern cancer biology
(Elsevier BV, 2014)Cancer nanotherapeutics are progressing at a steady rate; research and development in the field has experienced an exponential growth since early 2000’s. The path to the commercialization of oncology drugs is long and ... -
Cancer Stem Cell-Like Cells Derived from Malignant Peripheral Nerve Sheath Tumors
(Public Library of Science, 2011)This study aims to examine whether or not cancer stem cells exist in malignant peripheral nerve sheath tumors (MPNST). Cells of established lines, primary cultures and freshly dissected tumors were cultured in serum free ... -
Cancer survivor rehabilitation and recovery: Protocol for the Veterans Cancer Rehabilitation Study (Vet-CaRes)
(BioMed Central, 2013)Background: Cancer survivors are a rapidly growing and aging population in the U.S., but there are many challenges associated with the survivorship experience such as functional disabilities and psychosocial distress. When ... -
Candida albicans Infection of Caenorhabditis elegans Induces Antifungal Immune Defenses
(Public Library of Science, 2011)Candida albicans yeast cells are found in the intestine of most humans, yet this opportunist can invade host tissues and cause life-threatening infections in susceptible individuals. To better understand the host factors ...