Now showing items 240-259 of 18423

    • Access, quality, and costs of care at physician owned hospitals in the United States: observational study 

      Blumenthal, Daniel M; Orav, E John; Jena, Anupam B; Dudzinski, David M; Le, Sidney T; Jha, Ashish K (BMJ Publishing Group Ltd., 2015)
      Objective: To compare physician owned hospitals (POHs) with non-POHs on metrics around patient populations, quality of care, costs, and payments. Design: Observational study. Setting: Acute care hospitals in 95 hospital ...
    • The accessible chromatin landscape of the human genome 

      Thurman, Robert E.; Rynes, Eric; Humbert, Richard; Vierstra, Jeff; Maurano, Matthew T.; Haugen, Eric; Sheffield, Nathan C.; Stergachis, Andrew B.; Wang, Hao; Vernot, Benjamin; Garg, Kavita; Sandstrom, Richard; Bates, Daniel; Canfield, Theresa K.; Diegel, Morgan; Dunn, Douglas; Ebersol, Abigail K.; Frum, Tristan; Giste, Erika; Harding, Lisa; Johnson, Audra K.; Johnson, Ericka M.; Kutyavin, Tanya; Lajoie, Bryan; Lee, Bum-Kyu; Lee, Kristen; London, Darin; Lotakis, Dimitra; Neph, Shane; Neri, Fidencio; Nguyen, Eric D.; Reynolds, Alex P.; Roach, Vaughn; Safi, Alexias; Sanchez, Minerva E.; Sanyal, Amartya; Shafer, Anthony; Simon, Jeremy M.; Song, Lingyun; Vong, Shinny; Weaver, Molly; Zhang, Zhancheng; Zhang, Zhuzhu; Lenhard, Boris; Tewari, Muneesh; Dorschner, Michael O.; Hansen, R. Scott; Navas, Patrick A.; Stamatoyannopoulos, George; Iyer, Vishwanath R.; Lieb, Jason D.; Sunyaev, Shamil R.; Akey, Joshua M.; Sabo, Peter J.; Kaul, Rajinder; Furey, Terrence S.; Dekker, Job; Crawford, Gregory E.; Stamatoyannopoulos, John A. (2013)
      DNaseI hypersensitive sites (DHSs) are markers of regulatory DNA and have underpinned the discovery of all classes of cis-regulatory elements including enhancers, promoters, insulators, silencers, and locus control regions. ...
    • Accessory Breast Tissue 

      Patel, Priti P.; Ibrahim, Ahmed Mohamed Said; Zhang, Jacob; Nguyen, John T.; Lin, Samuel J.; Lee, Bernard Travis (Open Science Company, LLC, 2012)
    • Acclimatization across space and time in the effects of temperature on mortality: a time-series analysis 

      Lee, Mihye; Nordio, Francesco; Zanobetti, Antonella; Kinney, Patrick; Vautard, Robert; Schwartz, Joel (BioMed Central, 2014)
      Background: Climate change has increased the days of unseasonal temperature. Although many studies have examined the association between temperature and mortality, few have examined the timing of exposure where whether ...
    • Accounting for Comorbidity in Assessing the Burden of Epilepsy Among US Adults: Results from the National Comorbidity Survey Replication (NCS-R) 

      Kessler, Ronald; Lane, Michael C.; Shahly, Vicki; Stang, Paul E. (Nature Publishing Group, 2012)
      Although epilepsy is associated with substantial role impairment, it is also highly comorbid with other physical and mental disorders, making unclear the extent to which impairments associated with epilepsy are actually ...
    • Accumulated Lead Exposure and Risk of Age-Related Cataract in Men 

      Schaumberg, Debra Ann; Mendes, Flavia; Balaram, Mini; Dana, Reza; Sparrow, David; Hu, Howard (American Medical Association (AMA), 2004)
      Context Low-level lead exposure may increase the risk for a number of chronic age-related diseases. Several studies have documented the presence of lead in lenses with cataract. The intrusion of lead into the lens may alter ...
    • Accumulation of Metabolic Cardiovascular Risk Factors in Black and White Young Adults Over 20 Years 

      Paynter, Nina P.; Kiefe, Catarina I.; Lewis, Cora E.; Loria, Catherine M.; Goff, David C.; Lloyd‐Jones, Donald M. (Blackwell Publishing Ltd, 2015)
      Background: Cross‐sectional clustering of metabolic risk factors for cardiovascular disease in middle‐aged adults is well described, but less is known regarding the order in which risk factors develop through young adulthood ...
    • Accumulation of Protease Mutations among Patients Failing Second-Line Antiretroviral Therapy and Response to Salvage Therapy in Nigeria 

      Rawizza, Holly E.; Chaplin, Beth; Meloni, Seema T.; Darin, Kristin M.; Olaitan, Oluremi; Scarsi, Kimberly K.; Onwuamah, Chika K.; Audu, Rosemary A.; Chebu, Philippe R.; Imade, Godwin E.; Okonkwo, Prosper; Kanki, Phyllis J. (Public Library of Science, 2013)
      Background: To date, antiretroviral therapy (ART) guidelines and programs in resource-limited settings (RLS) have focused on 1st- and 2nd-line (2 L) therapy. As programs approach a decade of implementation, policy regarding ...
    • Accumulation of the Vitamin D Precursor Cholecalciferol Antagonizes Hedgehog Signaling to Impair Hemogenic Endothelium Formation 

      Cortes, Mauricio; Liu, Sarah Y.; Kwan, Wanda; Alexa, Kristen; Goessling, Wolfram; North, Trista E. (Elsevier, 2015)
      Summary Hematopoietic stem and progenitor cells (HSPCs) are born from hemogenic endothelium in the dorsal aorta. Specification of this hematopoietic niche is regulated by a signaling axis using Hedgehog (Hh) and Notch, ...
    • Accumulation of Tissue Factor into Developing Thrombi in Vivo Is Dependent upon Microparticle P-Selectin Glycoprotein Ligand 1 and Platelet P-Selectin 

      Falati, Shahrokh; Liu, Qingde; Gross, Peter; Merrill-Skoloff, Glenn; Chou, Janet; Vandendries, Erik; Celi, Alessandro; Croce, Kevin; Furie, Barbara C.; Furie, Bruce (Rockefeller University Press, 2003)
      Using a laser-induced endothelial injury model, we examined thrombus formation in the microcirculation of wild-type and genetically altered mice by real-time in vivo microscopy to analyze this complex physiologic process ...
    • Accuracy and Precision in Quantitative Fluorescence Microscopy 

      Waters, Jennifer Catherine (The Rockefeller University Press, 2009)
      The light microscope has long been used to document the localization of fluorescent molecules in cell biology research. With advances in digital cameras and the discovery and development of genetically encoded fluorophores, ...
    • Accuracy and reproducibility of automated, standardized coronary transluminal attenuation gradient measurements 

      Chatzizisis, Yiannis; George, Elizabeth; Cai, Tianrun; Fulwadhva, Urvi P; Kumamaru, Kanako; Schultz, Kurt; Fujisawa, Yasuko; Rassi, Carlos; Steigner, Michael L.; Mather, Richard T.; Blankstein, Ron; Rybicki, Frank; Mitsouras, Dimitrios (Springer Nature, 2014)
      Purpose Coronary Computed Tomography Angiography (CCTA) contrast opacification gradients, or Transluminal Attenuation Gradients (TAG) offer incremental value to predict functionally significant lesions. This study ...
    • Accuracy of administrative data for surveillance of healthcare-associated infections: a systematic review 

      van Mourik, Maaike S M; van Duijn, Pleun Joppe; Moons, Karel G M; Bonten, Marc J M; Lee, Grace M (BMJ Publishing Group, 2015)
      Objective: Measuring the incidence of healthcare-associated infections (HAI) is of increasing importance in current healthcare delivery systems. Administrative data algorithms, including (combinations of) diagnosis codes, ...
    • Accuracy of CT Colonography for Detection of Polypoid and Nonpolypoid Neoplasia by Gastroenterologists and Radiologists: A Nationwide Multicenter Study in Japan 

      Nagata, Koichi; Endo, Shungo; Honda, Tetsuro; Yasuda, Takaaki; Hirayama, Michiaki; Takahashi, Sho; Kato, Takashi; Horita, Shoichi; Furuya, Ken; Kasai, Kenji; Matsumoto, Hiroshi; Kimura, Yoshiki; Utano, Kenichi; Sugimoto, Hideharu; Kato, Hiroyuki; Yamada, Rieko; Yamamichi, Junta; Shimamoto, Takeshi; Ryu, Yasuji; Matsui, Osamu; Kondo, Hitoshi; Doi, Ayako; Abe, Taro; Yamano, Hiro-o; Takeuchi, Ken; Hanai, Hiroyuki; Saida, Yukihisa; Fukuda, Katsuyuki; Näppi, Janne; Yoshida, Hiroyuki (Nature Publishing Group, 2017)
      OBJECTIVES: The objective of this study was to assess prospectively the diagnostic accuracy of computer-assisted computed tomographic colonography (CTC) in the detection of polypoid (pedunculated or sessile) and nonpolypoid ...
    • Accuracy of Electrocardiographic Criteria for Atrial Enlargement: Validation with Cardiovascular Magnetic Resonance 

      Tsao, Connie Wei-Lee; Josephson, Mark; Hauser, Thomas Henry; O'Halloran, Thomas D.; Agarwal, Anupam; Manning, Warren J.; Yeon, Susan B. (BioMed Central, 2008)
      Background: Anatomic atrial enlargement is associated with significant morbidity and mortality. However, atrial enlargement may not correlate with clinical measures such as electrocardiographic (ECG) criteria. Past studies ...
    • Accuracy of epidemiological inferences based on publicly available information: retrospective comparative analysis of line lists of human cases infected with influenza A(H7N9) in China 

      Lau, Eric HY; Zheng, Jiandong; Tsang, Tim K; Liao, Qiaohong; Lewis, Bryan; Brownstein, John S; Sanders, Sharon; Wong, Jessica Y; Mekaru, Sumiko R; Rivers, Caitlin; Wu, Peng; Jiang, Hui; Li, Yu; Yu, Jianxing; Zhang, Qian; Chang, Zhaorui; Liu, Fengfeng; Peng, Zhibin; Leung, Gabriel M; Feng, Luzhao; Cowling, Benjamin J; Yu, Hongjie (BioMed Central, 2014)
      Background: Appropriate public health responses to infectious disease threats should be based on best-available evidence, which requires timely reliable data for appropriate analysis. During the early stages of epidemics, ...
    • Accuracy of Inferior Vena Cava Ultrasound for Predicting Dehydration in Children with Acute Diarrhea in Resource-Limited Settings 

      Modi, Payal; Glavis-Bloom, Justin; Nasrin, Sabiha; Guy, Allysia; Chowa, Erika P.; Dvor, Nathan; Dworkis, Daniel A.; Oh, Michael; Silvestri, David M.; Strasberg, Stephen; Rege, Soham; Noble, Vicki E.; Alam, Nur H.; Levine, Adam C. (Public Library of Science, 2016)
      Introduction: Although dehydration from diarrhea is a leading cause of morbidity and mortality in children under five, existing methods of assessing dehydration status in children have limited accuracy. Objective: To assess ...
    • The Accuracy of the Physical Examination for the Diagnosis of Midlumbar and Low Lumbar Nerve Root Impingement 

      Suri, Pradeep; Rainville, James; Katz, Jeffrey; Jouve, Cristin; Hartigan, Carol; Limke, Janet; Pena, Enrique; Li, Ling; Swaim, Bryan; Hunter, David J. (Ovid Technologies (Wolters Kluwer Health), 2011)
      Study Design: Cross-sectional study with prospective recruitment. Objective: To determine the accuracy of the physical examination for the diagnosis of midlumbar nerve root impingement (L2, L3, or L4), low lumbar nerve ...
    • Accurate measurement of pancreatic islet β-cell mass using a second-generation fluorescent exendin-4 analog 

      Reiner, Thomas; Thurber, Greg; Gaglia, Jason; Vinegoni, Claudio; Liew, Chong Wee; Upadhyay, Rabi; Kohler, Rainer H.; Li, Li; Kulkarni, Rohit N.; Benoist, Christophe; Mathis, Diane; Weissleder, Ralph (National Academy of Sciences, 2011)
    • Accurate Whole Genome Sequencing as the Ultimate Genetic Test 

      Drmanac, R.; Peters, B. A.; Church, George McDonald; Reid, Clifford; Xu, Xun (American Association for Clinical Chemistry (AACC), 2014)