Now showing items 5954-5973 of 18424

    • Evaluation in Mice of a Conjugate Vaccine for Cholera Made from Vibrio cholerae O1 (Ogawa) O-Specific Polysaccharide 

      Alam, Mohammad Murshid; Bufano, Megan Kelly; Xu, Peng; Kalsy, Anuj; Yu, Y.; Freeman, Y. Wu; Sultana, Tania; Rashu, Md. Rasheduzzaman; Desai, Ishaan; Eckhoff, Grace; Leung, Daniel T.; Charles, Richelle C.; LaRocque, Regina C.; Harris, Jason B.; Clements, John D.; Calderwood, Stephen B.; Qadri, Firdausi; Vann, W. F.; Kováč, Pavol; Ryan, Edward T. (Public Library of Science, 2014)
      Background: Protective immunity against cholera is serogroup specific. Serogroup specificity in Vibrio cholerae is determined by the O-specific polysaccharide (OSP) of lipopolysaccharide (LPS). Generally, polysaccharides ...
    • Evaluation of 3D fluoroscopic image generation from a single planar treatment image on patient data with a modified XCAT phantom 

      Mishra, Pankaj; Li, Ruijiang; James, Sara St; Mak, Raymond Heungwing; Williams, Christopher Leigh; Yue, Yong; Berbeco, Ross I.; Lewis, John Austin (IOP Publishing, 2013)
      Accurate understanding and modeling of respiration-induced uncertainties is essential in image-guided radiotherapy. Explicit modeling of overall lung motion and interaction among different organs promises to be a useful ...
    • Evaluation of a Large-Scale Biomedical Data Annotation Initiative 

      Lacson, Ronilda C.; Pitzer, Erik; Hinske, Christian; Galante, Pedro; Ohno-Machado, Lucila (BioMed Central, 2009)
      Background: This study describes a large-scale manual re-annotation of data samples in the Gene Expression Omnibus (GEO), using variables and values derived from the National Cancer Institute thesaurus. A framework is ...
    • Evaluation of a new approach to compute intervertebral disc height measurements from lateral radiographic views of the spine 

      Allaire, Brett T.; DePaolis Kaluza, M. Clara; Bruno, Alexander G.; Samelson, Elizabeth J.; Kiel, Douglas P; Anderson, Dennis Earl; Bouxsein, Mary Larsen (Springer Nature, 2016)
      Purpose Current standard methods to quantify disc height, namely distortion compensated Roentgen analysis (DCRA), have been mostly utilized in the lumbar and cervical spine and have strict exclusion criteria. Specifically, ...
    • Evaluation of a Novel Inaba Cholera Conjugate Vaccine in Mice 

      Eckhoff, Grace (2015-06-08)
      Vibrio cholerae is a non-invasive Gram-negative enteric pathogen that causes cholera, a severe dehydrating diarrheal illness of humans. Cholera is responsible for substantial morbidity and mortality in both endemic and ...
    • Evaluation of a questionnaire to assess selected infectious diseases and their risk factors: Findings of a multicenter study 

      Sievers, Claudia; Akmatov, Manas K.; Kreienbrock, Lothar; Hille, Katja; Ahrens, Wolfgang; Günther, Kathrin; Flesch-Janys, Dieter; Obi, Nadia; Michels, Karin B.; Fricke, Julia; Greiser, Karin H.; Kaaks, Rudolf; Peter, Hans-Hartmut; Pessler, Frank; Nieters, Alexandra; Krause, Gérard (Springer Berlin Heidelberg, 2014)
      Background/objectives The risk to die from an infectious disease in Germany has been continuously decreasing over the last century. Since infections are, however, not only causes of death but risk factors for diseases like ...
    • Evaluation of a Typhoid/Paratyphoid Diagnostic Assay (TPTest) Detecting Anti-Salmonella IgA in Secretions of Peripheral Blood Lymphocytes in Patients in Dhaka, Bangladesh 

      Khanam, Farhana; Sheikh, Alaullah; Sayeed, Md. Abu; Bhuiyan, Md. Saruar; Choudhury, Feroza Kaneez; Salma, Umme; Pervin, Shahnaz; Sultana, Tania; Ahmed, Dilruba; Goswami, Doli; Hossain, Md. Lokman; Mamun, K. Z.; Charles, Richelle C.; Brooks, W. Abdullah; Calderwood, Stephen B.; Cravioto, Alejandro; Ryan, Edward T.; Qadri, Firdausi (Public Library of Science, 2013)
      Background: Rapid and reliable diagnostic assays for enteric (typhoid and paratyphoid) fever are urgently needed. We report the characterization of novel approach utilizing lymphocyte secretions, for diagnosing patients ...
    • Evaluation of a web-based portal to improve resident education by neonatology fellows 

      Lakshmanan, Ashwini; Leeman, Kristen T.; Brodsky, Dara; Parad, Richard (Co-Action Publishing, 2014)
      Background: Integration of web-based educational tools into medical training has been shown to increase accessibility of resources and optimize teaching. We developed a web-based educational portal (WBEP) to support teaching ...
    • Evaluation of actigraphy-measured sleep patterns among children with disabilities and associations with caregivers’ educational attainment: results from a cross-sectional study 

      Chen, Xiaoli; Velez, Juan Carlos; Barbosa, Clarita; Pepper, Micah; Gelaye, Bizu; Redline, Susan; Williams, Michelle A (BMJ Publishing Group, 2015)
      Objectives: To use wrist-actrigrphy to collect objective measures of sleep and to characterise actigraphy-measured sleep patterns among children with disabilities. We also assessed the extent to which, if at all, caregivers’ ...
    • Evaluation of an Automated Safety Surveillance System Using Risk Adjusted Sequential Probability Ratio Testing 

      Matheny, Michael E; Normand, Sharon-Lise Teresa; Gross, Thomas; Marinac-Dabic, Danica; Loyo-Berrios, Nilsa; Vidi, Venkatesan D; Donnelly, Sharon; Resnic, Frederic S. (BioMed Central, 2011)
      Background: Automated adverse outcome surveillance tools and methods have potential utility in quality improvement and medical product surveillance activities. Their use for assessing hospital performance on the basis of ...
    • Evaluation of an Electricity-free, Culture-based Approach for Detecting Typhoidal Salmonella Bacteremia during Enteric Fever in a High Burden, Resource-limited Setting 

      Andrews, Jason R.; Prajapati, Krishna G.; Eypper, Elizabeth; Shrestha, Poojan; Shakya, Mila; Pathak, Kamal R.; Joshi, Niva; Tiwari, Priyanka; Risal, Manisha; Koirala, Samir; Karkey, Abhilasha; Dongol, Sabina; Wen, Shawn; Smith, Amy B.; Maru, Duncan; Basnyat, Buddha; Baker, Stephen; Farrar, Jeremy; Ryan, Edward T.; Hohmann, Elizabeth; Arjyal, Amit (Public Library of Science, 2013)
      Background: In many rural areas at risk for enteric fever, there are few data on Salmonella enterica serotypes Typhi (S. Typhi) and Paratyphi (S. Paratyphi) incidence, due to limited laboratory capacity for microbiologic ...
    • Evaluation of an Online Platform for Multiple Sclerosis Research: Patient Description, Validation of Severity Scale, and Exploration of BMI Effects on Disease Course 

      Musallam, Alexander; Vaughan, Timothy; Wicks, Paul; Bove, Riley Marie; Secor, Elizabeth; Healy, Brian Curran; Glanz, Bonnie; Greeke, Emily Elizabeth; Weiner, Howard Lee; Chitnis, Tanuja; De Jager, Philip Lawrence (Public Library of Science, 2013)
      Objectives: To assess the potential of an online platform, PatientsLikeMe.com (PLM), for research in multiple sclerosis (MS). An investigation of the role of body mass index (BMI) on MS disease course was conducted to ...
    • Evaluation of Association of HNF1B Variants with Diverse Cancers: Collaborative Analysis of Data from 19 Genome-Wide Association Studies 

      Elliott, Katherine S.; Zeggini, Eleftheria; McCarthy, Mark I.; Gudmundsson, Julius; Sulem, Patrick; Stacey, Simon N.; Thorlacius, Steinunn; Amundadottir, Laufey; Grönberg, Henrik; Xu, Jianfeng; Gaborieau, Valerie; Eeles, Rosalind A.; Neal, David E.; Donovan, Jenny L.; Hamdy, Freddie C.; Muir, Kenneth; Hwang, Shih-Jen; Spitz, Margaret R.; Zanke, Brent; Carvajal-Carmona, Luis; Brown, Kevin M.; Hayward, Nicholas K.; Macgregor, Stuart; Tomlinson, Ian P. M.; Lemire, Mathieu; Amos, Christopher I.; Murabito, Joanne M.; Isaacs, William B.; Easton, Douglas F.; Brennan, Paul; Barkardottir, Rosa B.; Gudbjartsson, Daniel F.; Rafnar, Thorunn; Chanock, Stephen J.; Stefansson, Kari; Australian Melanoma Family Study Investigators; The PanScan Consortium; Hunter, David J.; Ioannidis, John (Public Library of Science, 2010)
      Background: Genome-wide association studies have found type 2 diabetes-associated variants in the HNF1B gene to exhibit reciprocal associations with prostate cancer risk. We aimed to identify whether these variants may ...
    • Evaluation of Biomaterials for Bladder Augmentation using Cystometric Analyses in Various Rodent Models 

      Tu, Duong D; Seth, Abhishek; Gil, Eun Seok; Kaplan, David L.; Mauney, Joshua Robert; Estrada, Carlos R. (MyJove Corporation, 2012)
      Renal function and continence of urine are critically dependent on the proper function of the urinary bladder, which stores urine at low pressure and expels it with a precisely orchestrated contraction. A number of congenital ...
    • Evaluation of Cancer Metabolomics Using ex vivo High Resolution Magic Angle Spinning (HRMAS) Magnetic Resonance Spectroscopy (MRS) 

      Fuss, Taylor L.; Cheng, Leo L. (MDPI, 2016)
      According to World Health Organization (WHO) estimates, cancer is responsible for more deaths than all coronary heart disease or stroke worldwide, serving as a major public health threat around the world. High resolution ...
    • Evaluation of Candidate Stromal Epithelial Cross-Talk Genes Identifies Association between Risk of Serous Ovarian Cancer and TERT, a Cancer Susceptibility “Hot-Spot” 

      Johnatty, Sharon E.; Beesley, Jonathan; Chen, Xiaoqing; Macgregor, Stuart; Duffy, David L.; Spurdle, Amanda B.; deFazio, Anna; Gava, Natalie; Webb, Penelope M.; Rossing, Mary Anne; Doherty, Jennifer Anne; Goodman, Marc T.; Lurie, Galina; Wilkens, Lynne R.; Ness, Roberta B.; Moysich, Kirsten B.; Chang-Claude, Jenny; Wang-Gohrke, Shan; Garcia-Closas, Montserrat; Yang, Hannah; Lissowska, Jolanta; Chanock, Stephen J.; Pharoah, Paul D.; Song, Honglin; Whitemore, Alice S.; Pearce, Celeste L.; Stram, Daniel O.; Wu, Anna H.; Pike, Malcolm C.; Gayther, Simon A.; Ramus, Susan J.; Menon, Usha; Gentry-Maharaj, Aleksandra; Anton-Culver, Hoda; Ziogas, Argyrios; Hogdall, Estrid; Kjaer, Susanne K.; Hogdall, Claus; Berchuck, Andrew; Schildkraut, Joellen M.; Iversen, Edwin S.; Moorman, Patricia G.; Phelan, Catherine M.; Sellers, Thomas A.; Cunningham, Julie M.; Vierkant, Robert A.; Rider, David N.; Goode, Ellen L.; Haviv, Izhak; Chenevix-Trench, Georgia; Thompson, Pamela J.; Cramer, Daniel William; Terry, Kathryn Lynne; Hankinson, Susan Elizabeth; Tworoger, Shelley Slate (Public Library of Science, 2010)
      We hypothesized that variants in genes expressed as a consequence of interactions between ovarian cancer cells and the host micro-environment could contribute to cancer susceptibility. We therefore used a two-stage approach ...
    • Evaluation of current algorithms for segmentation of scar tissue from late Gadolinium enhancement cardiovascular magnetic resonance of the left atrium: an open-access grand challenge 

      Karim, Rashed; Housden, R James; Balasubramaniam, Mayuragoban; Chen, Zhong; Perry, Daniel; Uddin, Ayesha; Al-Beyatti, Yosra; Palkhi, Ebrahim; Acheampong, Prince; Obom, Samantha; Hennemuth, Anja; Lu, YingLi; Bai, Wenjia; Shi, Wenzhe; Gao, Yi; Peitgen, Heinz-Otto; Radau, Perry; Razavi, Reza; Tannenbaum, Allen; Rueckert, Daniel; Cates, Josh; Schaeffter, Tobias; Peters, Dana; MacLeod, Rob; Rhode, Kawal (BioMed Central, 2013)
      Background: Late Gadolinium enhancement (LGE) cardiovascular magnetic resonance (CMR) imaging can be used to visualise regions of fibrosis and scarring in the left atrium (LA) myocardium. This can be important for treatment ...
    • Evaluation of cystatin C as an early biomarker of cadmium nephrotoxicity in the rat 

      Prozialeck, Walter C.; VanDreel, Aaron; Ackerman, Christopher D.; Stock, Ian; Papaeliou, Alexander; Yasmine, Christian; Wilson, Kristen; Lamar, Peter C.; Sears, Victoria L.; Gasiorowski, Joshua Z.; DiNovo, Karyn M.; Vaidya, Vishal S.; Edwards, Joshua R. (Springer Netherlands, 2015)
      Cadmium (Cd) is a nephrotoxic environmental pollutant that causes insidious injury to the proximal tubule that results in severe polyuria and proteinuria. Cystatin C is a low molecular weight protein that is being evaluated ...
    • Evaluation of Delirium in Critically Ill Patients: Validation of the Confusion Assessment Method for the Intensive Care Unit (CAM-ICU) 

      Ely, E. Wesley; Margolin, Richard; Francis, Joseph; May, Lisa; Truman, Brenda; Dittus, Robert; Speroff, Theodore; Gautam, Shiva; Bernard, Gordon R.; Inouye, Sharon (Ovid Technologies (Wolters Kluwer Health), 2001-07)
      Objective: To develop and validate an instrument for use in the intensive care unit to accurately diagnose delirium in critically ill patients who are often nonverbal because of mechanical ventilation. Design: Prospective ...
    • Evaluation of Denoising Algorithms for Biological Electron Tomography 

      Narasimha, Rajesh; Aganj, Iman; Bennett, Adam E.; Borgnia, Mario J.; Zabransky, Daniel; Sapiro, Guillermo; McLaughlin, Steven W.; Milne, Jacqueline L.S.; Subramaniam, Sriram (Elsevier BV, 2008-10)
      Tomograms of biological specimens derived using transmission electron microscopy can be intrinsically noisy due to the use of low electron doses, the presence of a “missing wedge” in most data collection schemes, and ...