Browsing Harvard Medical School by Title
Now showing items 8738-8757 of 18428
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Improved Late Gadolinium Enhancement Imaging of Left Ventricle with Isotropic Spatial Resolution
(BioMed Central, 2012) -
Improved Long-term Expression from Helper Virus-free HSV-1 Vectors Packaged Using Combinations of Mutated HSV-1 Proteins that Include the UL13 Protein Kinase and Specific Components of the VP16 Transcriptional Complex
(BioMed Central, 2009)Background: Herpes Simplex Virus (HSV-1) gene expression is thought to shut off recombinant gene expression from HSV-1 vectors; however, in a helper virus-free HSV-1 vector system, a number of promoters support only ... -
Improved Long-Term Imaging of Embryos with Genetically Encoded α-Bungarotoxin
(Public Library of Science, 2015)Rapid advances in microscopy and genetic labeling strategies have created new opportunities for time-lapse imaging of embryonic development. However, methods for immobilizing embryos for long periods while maintaining ... -
Improved Navigator-Gated Motion Compensation in Cardiac MR Using Additional Constraint of Magnitude of Motion-Corrupted Data
(BioMed Central, 2012)Background. In conventional prospective respiratory navigator (NAV) acquisitions, 40-60% of the acquired data are discarded resulting in low efficiency and long scan times [1,2].Compressed-sensing Motion Compensation (CosMo) ... -
Improved Outcome Prediction Using CT Angiography in Addition to Standard Ischemic Stroke Assessment: Results from the STOPStroke Study
(Public Library of Science, 2012)Purpose: To improve ischemic stroke outcome prediction using imaging information from a prospective cohort who received admission CT angiography (CTA). Methods: In a prospectively designed study, 649 stroke patients diagnosed ... -
An improved predictive recognition model for Cys2-His2 zinc finger proteins
(Oxford University Press, 2014)Cys2-His2 zinc finger proteins (ZFPs) are the largest family of transcription factors in higher metazoans. They also represent the most diverse family with regards to the composition of their recognition sequences. Although ... -
An improved ScoreCard to assess the differentiation potential of human pluripotent stem cells
(2015)Research on human pluripotent stem cells has been hampered by the lack of a standardized, quantitative, scalable assay of pluripotency. We have previously described an assay called ScoreCard that used gene expression ... -
Improved Somatic Mutagenesis in Zebrafish Using Transcription Activator-Like Effector Nucleases (TALENs)
(Public Library of Science, 2012)Zinc Finger Nucleases (ZFNs) made by Context-Dependent Assembly (CoDA) and Transcription Activator-Like Effector Nucleases (TALENs) provide robust and user-friendly technologies for efficiently inactivating genes in ... -
Improved Therapeutic Monitoring With Several Interventions
(American Medical Association (AMA), 2006)Background Medication errors are frequently related to failure to appropriately select medications or adjust for laboratory parameters. Differences between guideline recommendations and actual frequency of therapeutic ... -
Improved tracking of sevoflurane anesthetic states with drug-specific machine learning models
(IOP Publishing, 2020-08-04) -
Improved Tumor Oxygenation and Survival in Glioblastoma Patients Who Show Increased Blood Perfusion After Cediranib and Chemoradiation
(National Academy of Sciences, 2013-11-19)Antiangiogenic therapy has shown clear activity and improved survival benefit for certain tumor types. However, an incomplete understanding of the mechanisms of action of antiangiogenic agents has hindered optimization and ... -
Improved tumor vascularization after anti-VEGF therapy with carboplatin and nab-paclitaxel associates with survival in lung cancer
(National Academy of Sciences, 2015)Addition of anti-VEGF antibody therapy to standard chemotherapies has improved survival and is an accepted standard of care for advanced non-small cell lung cancer (NSCLC). However, the mechanisms by which anti-VEGF therapy ... -
Improved Vascular Engraftment and Graft Function After Inhibition of the Angiostatic Factor Thrombospondin-1 in Mouse Pancreatic Islets
(American Diabetes Association, 2008)Objective: Insufficient development of a new intra-islet capillary network after transplantation may be one contributing factor to the failure of islet grafts in clinical transplantation. The present study tested the ... -
Improvement and Emergence of Insulin Restriction in Women With Type 1 Diabetes
(American Diabetes Association, 2011)OBJECTIVE To determine the distinguishing characteristics of women who report stopping insulin restriction at 11 years of follow-up from those continuing to endorse insulin restriction as well as those characteristics ... -
Improvement in kidney transplantation in the Balkans after the Istanbul Declaration: where do we stand today?
(Oxford University Press, 2015)Due to the limited access to kidney transplantation (KTx) in developing countries, desperate patients have engaged in the purchase and sale of kidneys. In 2004, the World Health Assembly urged member states to protect the ... -
Improvement of a face perception deficit via subsensory galvanic vestibular stimulation
(Cambridge University Press, 2005)The remediative effect of galvanic vestibular stimulation (GVS) was investigated in a patient who, following right hemisphere damage, is profoundly unable to recognize faces. We administered a two-alternative forced choice ... -
Improvement of Insulin Sensitivity by Isoenergy High Carbohydrate Traditional Asian Diet: A Randomized Controlled Pilot Feasibility Study
(Public Library of Science, 2014)The prevalence of diabetes is rising dramatically among Asians, with increased consumption of the typical Western diet as one possible cause. We explored the metabolic responses in East Asian Americans (AA) and Caucasian ... -
Improvement of Myocardial Perfusion Reserve Detected by Cardiovascular Magnetic Resonance After Direct Endomyocardial Implantation of Autologous Bone Marrow Cells in Patients With Severe Coronary Artery Disease
(BioMed Central, 2010)Background: Recent studies suggested that bone marrow (BM) cell implantation in patients with severe chronic coronary artery disease (CAD) resulted in modest improvement in symptoms and cardiac function. This study sought ... -
Improvements in newborn care and newborn resuscitation following a quality improvement program at scale: results from a before and after study in Tanzania
(BioMed Central, 2014)Background: Every year, more than a million of the world’s newborns die on their first day of life; as many as two-thirds of these deaths could be saved with essential care at birth and the early newborn period. Simple ... -
Improving Access to Medicines in Low and Middle Income Countries: Corporate Responsibilities in Context
(Dr. Zaheer-Ud-Din Babar, 2012)More than two billion people in low- and middle-income countries (LMIC) lack adequate access to essential medicines. In this paper, we make strong public health, human rights and economic arguments for improving access to ...