Now showing items 13173-13192 of 18424

    • Plant-Based Dietary Patterns and Incidence of Type 2 Diabetes in US Men and Women: Results from Three Prospective Cohort Studies 

      Satija, Ambika; Bhupathiraju, Shilpa N.; Rimm, Eric B.; Spiegelman, Donna; Chiuve, Stephanie E.; Borgi, Lea; Willett, Walter C.; Manson, JoAnn E.; Sun, Qi; Hu, Frank B. (Public Library of Science, 2016)
      Background: Plant-based diets have been recommended to reduce the risk of type 2 diabetes (T2D). However, not all plant foods are necessarily beneficial. We examined the association of an overall plant-based diet and ...
    • Planum Temporale and Heschl Gyrus Volume Reduction in Schizophrenia 

      Hirayasu, Yoshio; McCarley, Robert William; Salisbury, Dean F.; Tanaka, Shin; Soo Kwon, Jun; Frumin, Melissa; Snyderman, Danielle; Yurgelun-Todd, Deborah; Kikinis, Ron; Jolesz, Ferenc A.; Shenton, Martha Elizabeth (American Medical Association, 2000)
      Background: Magnetic resonance imaging studies in schizophrenia have revealed abnormalities in temporal lobe structures, including the superior temporal gyrus. More specifically, abnormalities have been reported in the ...
    • Plasma 25-Hydroxyvitamin D and Progression to Diabetes in Patients at Risk for Diabetes 

      Pittas, Anastassios G.; Nelson, Jason; Mitri, Joanna; Hillmann, William; Garganta, Cheryl; Nathan, David Matthew; Hu, Frank B.; Dawson-Hughes, Bess (American Diabetes Association, 2012)
      OBJECTIVE To investigate the association between vitamin D status, assessed by plasma 25-hydroxyvitamin D, and risk of incident diabetes. RESEARCH DESIGN AND METHODS Prospective observational study with a mean follow-up ...
    • Plasma 25-hydroxyvitamin D and risk of premenstrual syndrome in a prospective cohort study 

      Bertone-Johnson, Elizabeth R; Johnson, Susan R; Hankinson, Susan E; Forger, Nancy G; Powers, Sally I; Willett, Walter C; Manson, JoAnn E (BioMed Central, 2014)
      Background: Moderate to severe premenstrual syndrome (PMS) affects 8–20 percent of premenopausal women. Previous studies suggest that high dietary vitamin D intake may reduce risk. However, vitamin D status is influenced ...
    • Plasma 25-hydroxyvitamin D concentration and metabolic syndrome among middle-aged and elderly Chinese individuals 

      Yu, Zhijie; Pan, An; Franco, Oscar H.; Li, Huaixing; Yang, Xilin; Lin, Xu; Lu, Ling; Hu, Frank B.; Li, Xiaoying; Chen, Yan (American Diabetes Association, 2009)
      OBJECTIVE—To evaluate the association between 25-hydroxyvitamin D [25(OH)D] and metabolic syndrome in the Chinese population. RESEARCH DESIGN AND METHODS—Plasma 25(OH)D was measured in a cross-sectional sample of 1,443 men ...
    • A Plasma Biomarker Signature of Immune Activation in HIV Patients on Antiretroviral Therapy 

      Kamat, Anupa U; Misra, Vikas; Cassol, Edana; Ancuta, Petronela; Yan, Zhenyu; Li, Cheng; Morgello, Susan; Gabuzda, Dana Helga (Public Library of Science, 2012)
      Background: Immune activation is a strong predictor of disease progression in HIV infection. Combinatorial plasma biomarker signatures that represent surrogate markers of immune activation in both viremic and aviremic HIV ...
    • Plasma Cathepsin S and Cathepsin S/Cystatin C Ratios Are Potential Biomarkers for COPD 

      Nakajima, Takahiro; Nakamura, Hidetoshi; Owen, Caroline A.; Yoshida, Shuichi; Tsuduki, Keishi; Chubachi, Shotaro; Shirahata, Toru; Mashimo, Shuko; Nakamura, Miho; Takahashi, Saeko; Minematsu, Naoto; Tateno, Hiroki; Fujishima, Seitaro; Asano, Koichiro; Celli, Bartolome R.; Betsuyaku, Tomoko (Hindawi Publishing Corporation, 2016)
      Purpose. This study aimed to examine whether plasma levels of cathepsin S or its inhibitor, cystatin C, may serve as biomarkers for COPD. Patients and Methods. We measured anthropometrics and performed pulmonary function ...
    • Plasma Cathepsin S and Cystatin C Levels and Risk of Abdominal Aortic Aneurysm: A Randomized Population–Based Study 

      Lv, Bing-Jie; Lindholt, Jes S.; Cheng, Xiang; Wang, Jing; Shi, Guo-Ping (Public Library of Science, 2012)
      Background: Human abdominal aortic aneurysm (AAA) lesions contain high levels of cathepsin S (CatS), but are deficient in its inhibitor, cystatin C. Whether plasma CatS and cystatin C levels are also altered in AAA patients ...
    • Plasma Concentrations of Soluble Endoglin versus Standard Evaluation in Patients with Suspected Preeclampsia 

      Rana, Sarosh; Cerdeira, Ana Sofia Teixeira de; Wenger, Julia; Salahuddin, Saira; Lim, Kee-Hak; Ralston, Steven Joseph; Thadhani, Ravi Ishwar; Karumanchi, Subbian Ananth (Public Library of Science, 2012)
      Background: The purpose of this study was to compare plasma soluble endoglin (sEng) levels with standard clinical evaluation or plasma levels of other angiogenic proteins [soluble fms-like tyrosine kinase 1 (sFlt1) and ...
    • Plasma Concentrations, Efficacy and Safety of Efavirenz in HIV-Infected Adults Treated for Tuberculosis in Cambodia (ANRS 1295-CIPRA KH001 CAMELIA Trial) 

      Borand, Laurence; Madec, Yoann; Laureillard, Didier; Chou, Monidarin; Marcy, Olivier; Pheng, Phearavin; Prak, Narom; Kim, Chindamony; Lak, Khemarin Kim; Hak, Chanroeun; Dim, Bunnet; Nerrienet, Eric; Fontanet, Arnaud; Sok, Thim; Goldfeld, Anne E.; Blanc, François-Xavier; Taburet, Anne-Marie (Public Library of Science, 2014)
      Objective: To assess efavirenz plasma concentrations and their association with treatment efficacy and tolerance of efavirenz 600 mg daily in HIV-tuberculosis co-infected patients. Methods: HIV-infected adults with CD4+ T ...
    • Plasma Corin Decreases After Coronary Artery Bypass Graft Surgery and Is Associated With Postoperative Heart Failure: A Pilot Study 

      Barnet, Caryn S.; Liu, Xiaoxiao; Body, Simon Christopher; Collard, Charles D.; Shernan, Stanton K.; Muehlschlegel, Jochen Daniel; Jarolim, Petr; Fox, Amanda A. (Elsevier BV, 2015)
      Objective: Corin is a natriuretic peptide-converting enzyme that cleaves precursor pro-B-type natriuretic peptide to active B-type natriuretic peptide (BNP) (diuretic, natriuretic, and vaso- dilatory properties). Increased ...
    • Plasma Fatty Acid Binding Protein 4 and Risk of Sudden Cardiac Death in Older Adults 

      Djoussé, Luc; Maziarz, Marlena; Biggs, Mary L.; Ix, Joachim H.; Zieman, Susan J.; Kizer, Jorge R.; Lemaitre, Rozenn N.; Mozaffarian, Dariush; Tracy, Russell P.; Mukamal, Kenneth J.; Siscovick, David S.; Sotoodehnia, Nona (Hindawi Publishing Corporation, 2013)
      Although fatty acid binding protein 4 (FABP4) may increase risk of diabetes and exert negative cardiac inotropy, it is unknown whether plasma concentrations of FABP4 are associated with incidence of sudden cardiac death ...
    • Plasma Gelsolin Depletion and Circulating Actin in Sepsis—A Pilot Study 

      Lee, Po-Shun; Patel, Sanjay R; Christiani, David C.; Bajwa, Ednan Khalid; Stossel, Thomas Peter; Waxman, Aaron Bradley (Public Library of Science, 2008)
      Background: Depletion of the circulating actin-binding protein, plasma gelsolin (pGSN) has been described in septic patients and animals. We hypothesized that the extent of pGSN reduction correlates with outcomes of septic ...
    • Plasma Heme Oxygenase-1 Concentration is Elevated in Individuals with Type 2 Diabetes Mellitus 

      Song, Fangfang; Li, Xiangyang; Rong, Shuang; Zhang, Muxun; Yao, Ping; Hao, Liping; Yang, Nianhong; Liu, Liegang; Bao, Wei; Yang, Wei; Hu, Frank B. (Public Library of Science, 2010)
      Background: Circulating concentrations of heme oxygenase-1 (HO-1) have been recently reported to be elevated in several chronic disorders. However, no study has ever examined the association between circulating HO-1 ...
    • Plasma Inflammatory Markers and the Risk of Developing Hypertension in Men 

      Sesso, Howard D; Jiménez, Monik C; Wang, Lu; Ridker, Paul M; Buring, Julie E; Gaziano, J Michael (John Wiley & Sons, Ltd, 2015)
      Background: Several cross-sectional, but few prospective, studies suggest that inflammation may be involved in the development of hypertension. We examined markers of inflammation—high-sensitivity C-reactive protein, ...
    • Plasma Interleukin-6 Concentrations, Metabolic Dysfunction, and Asthma Severity: A Cross-Sectional Analysis of Two Cohorts 

      Peters, Michael C; McGrath, Kelly Wong; Hawkins, Gregory A.; Hastie, Annette T; Levy, Bruce; Israel, Elliot; Phillips, Brenda R; Mauger, David T; Comhair, Suzy A.; Erzurum, Serpil C.; Johansson, Mats W.; Jarjour, Nizar N.; Coverstone, Andrea M; Castro, Mario; Holguin, Fernando; Wenzel, Sally E.; Woodruff, Prescott G.; Bleecker, Eugene R.; Fahy, John V (Elsevier BV, 2016-07-01)
      Background Severe asthma is a complex heterogeneous disease associated with older age and obesity. The presence of eosinophilic (type 2) inflammation in some but not all patients with severe asthma predicts responsiveness ...
    • Plasma Kallikrein Mediates Retinal Vascular Dysfunction and Induces Retinal Thickening in Diabetic Rats 

      Clermont, Allen Charles; Chilcote, Tamie J.; Kita, Takeshi; Liu, Jia; Riva, Priscilla; Sinha, Sukanto; Feener, Edward Paul (American Diabetes Association, 2011)
      Objective: Plasma kallikrein (PK) has been identified in vitreous fluid obtained from individuals with diabetic retinopathy and has been implicated in contributing to retinal vascular dysfunction. In this report, we examined ...
    • Plasma Kallikrein Mediates Vascular Endothelial Growth Factor–Induced Retinal Dysfunction and Thickening 

      Clermont, Allen Charles; Murugesan, Nivetha; Zhou, Qunfang; Kita, Takeshi; Robson, Peter A.; Rushbrooke, Louise J.; Evans, D. Michael; Aiello, Lloyd Paul; Feener, Edward Paul (Association for Research in Vision and Ophthalmology (ARVO), 2016)
      Purpose: Plasma kallikrein is a serine protease and circulating component of inflammation, which exerts clinically significant effects on vasogenic edema. This study examines the role of plasma kallikrein in VEGF-induced ...
    • Plasma kininogen and kininogen fragments are biomarkers of progressive renal decline in type-1 diabetes 

      Merchant, Michael L.; Niewczas, Monika; Ficociello, Linda H.; Lukenbill, Janice; Wilkey, Daniel W.; Li, Ming; Khundmiri, Syed J.; Warram, James H.; Krolewski, Andrzej S.; Klein, Jon B. (2013)
      The ability of microalbuminuria to predict early progressive renal function decline in type-1 diabetic patients has been questioned. To resolve this, we determined the plasma proteome differences between microalbuminuric ...
    • Plasma Leptin Levels in Children Hospitalized with Cholera in Bangladesh 

      Falkard, Brie; Uddin, Taher; Arifur Rahman, M.; Franke, Molly F.; Aktar, Amena; Uddin, Muhammad Ikhtear; Bhuiyan, Taufiqur Rahman; Leung, Daniel T.; Charles, Richelle C.; Larocque, Regina C.; Harris, Jason B.; Calderwood, Stephen B.; Qadri, Firdausi; Ryan, Edward T. (The American Society of Tropical Medicine and Hygiene, 2015)
      Vibrio cholerae, the cause of cholera, induces both innate and adaptive immune responses in infected humans. Leptin is a hormone that plays a role in both metabolism and mediating immune responses. We characterized leptin ...