Browsing Harvard Medical School by Title
Now showing items 16513-16532 of 18424
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Surgery plus anesthesia induces loss of attention in mice
(Frontiers Media S.A., 2015)There is a need to develop animal models to study postoperative delirium. Inattention is one of the symptoms of delirium. Increases in the levels of α-synuclein and S100β have been reported to be associated with delirium. ... -
Surgical and Functional Outcomes in Patients Undergoing Total Knee Replacement With Patient-Specific Implants Compared With “Off-the-Shelf” Implants
(SAGE Publications, 2015)Background: Total knee arthroplasty (TKA) instrumentation and implant designs have been evolving, with one of the current innovations being patient-specific implants (PSIs). Purpose To evaluate whether there is a significant ... -
Surgical Impact on Brain Tumor Invasion: A Physical Perspective
(BioMed Central, 2008)It is conventional strategy to treat highly malignant brain tumors initially with cytoreductive surgery followed by adjuvant radio- and chemotherapy. However, in spite of all such efforts, the patients' prognosis remains ... -
Surgical Intensive Care Unit Optimal Mobilisation Score (SOMS) trial: a protocol for an international, multicentre, randomised controlled trial focused on goal-directed early mobilisation of surgical ICU patients
(BMJ Publishing Group, 2013)Introduction: Immobilisation in the intensive care unit (ICU) leads to muscle weakness and is associated with increased costs and long-term functional disability. Previous studies showed early mobilisation of medical ICU ... -
Surgical management for displaced pediatric proximal humeral fractures: a cost analysis
(Springer Berlin Heidelberg, 2015)Purpose The purpose of this investigation was to determine which of the following methods of fixation, percutaneous pinning (PP) or intramedullary nailing (IMN), was more cost-effective in the treatment of displaced pediatric ... -
The Surgical Management of Fibrous Dysplasia of Bone
(BioMed Central, 2012)The surgical management of Polyostotic Fibrous Dysplasia (FD) of bone is technically demanding. The most effective methods to manage the associated bone deformity remain unclear. The marked variation in the degree and ... -
Surgical models of Roux-en-Y gastric bypass surgery and sleeve gastrectomy in rats and mice
(Springer Science and Business Media LLC, 2015-02-26)Bariatric surgery is the only definitive solution to the present obesity pandemic. These operations typically involve reconfiguration of gastrointestinal tract anatomy and impose profound metabolic and physiological benefits, ... -
Surgical Risks Associated with Winter Sport Tourism
(Public Library of Science, 2015)Background: Mass tourism during winter in mountain areas may cause significant clustering of body injuries leading to increasing emergency admissions at hospital. We aimed at assessing if surgical safety and efficiency was ... -
Surgical Site Infections: Volume-Outcome Relationship and Year-to-Year Stability of Performance Rankings
(Lippincott Williams & Wilkins, 2017)Background: Surgical site infection (SSI) rates are publicly reported as quality metrics and increasingly used to determine financial reimbursement. Objective: To evaluate the volume-outcome relationship as well as the ... -
Surgical Travellers: Tapestry to Bayeux
(Ulster Medical Society, 2014-09)The planning for surgery in war was revisited in 1937 when Ian Fraser was elected a member of the Surgical Travellers. At their 1938 Surgical Travellers meeting in Vienna, Ian and Eleanor Fraser were evicted from their ... -
Surgical Treatment of Early Stage Breast Cancer in Elderly: An International Comparison
(Springer US, 2011)Over 40% of breast cancer patients are diagnosed above the age of 65. Treatment of these elderly patients will probably vary over countries. The aim of this study was to make an international comparison (several European ... -
Surgical treatments on adult tethered cord syndrome: A retrospective study
(Wolters Kluwer Health, 2016)Abstract To investigate effects of surgical treatment on adult tethered cord syndrome (TCS). A retrospective analysis of 82 adult patients (17 male cases, 82% and 24 female cases, 59%) with TCS treated by surgery was ... -
Surgical Wound Infection: Epidemiology, Pathogenesis, Diagnosis and Management
(BioMed Central, 2006)Surgical wound infection remains a significant problem following an operation, although surveillance for such infections remains a challenge exacerbated by early discharge and outpatient surgery. The riskof such infections ... -
Surprise? Early visual novelty processing is not modulated by attention
(Wiley-Blackwell, 2010) -
The Surprising Negative Correlation of Gene Length and Optimal Codon Use - Disentangling Translational Selection From GC-biased Gene Conversion in Yeast
(BioMed Central, 2011)Background: Surprisingly, in several multi-cellular eukaryotes optimal codon use correlates negatively with gene length. This contrasts with the expectation under selection for translational accuracy. While suggested ... -
Surrogates of Long-Term Vitamin D Exposure and Ovarian Cancer Risk in Two Prospective Cohort Studies
(MDPI, 2013)Experimental evidence and ecologic studies suggest a protective role of vitamin D in ovarian carcinogenesis. However, epidemiologic studies using individual level data have been inconsistent. We evaluated ultraviolet (UV)-B ... -
Surveillance for Neisseria meningitidis Disease Activity and Transmission Using Information Technology
(Public Library of Science, 2015)Background: While formal reporting, surveillance, and response structures remain essential to protecting public health, a new generation of freely accessible, online, and real-time informatics tools for disease tracking ... -
Surveillance of an Online Social Network to Assess Population-level Diabetes Health Status and Healthcare Quality
(University of Illinois at Chicago Library, 2011)Objective: Test a novel health monitoring approach by engaging an international online diabetes social network (SN) in consented health surveillance. Methods: Collection of structured self-reports about preventive and ... -
Surveillance of medication use: early identification of poor adherence
(BMJ Group, 2012)Background: We sought to measure population-level adherence to antihyperlipidemics, antihypertensives, and oral hypoglycemics, and to develop a model for early identification of subjects at high risk of long-term poor ... -
Survey of Activated FLT3 Signaling in Leukemia
(Public Library of Science, 2011)Activating mutations of FMS-like tyrosine kinase-3 (FLT3) are found in approximately 30% of patients with acute myeloid leukemia (AML). FLT3 is therefore an attractive drug target. However, the molecular mechanisms by which ...