Browsing Harvard Medical School by Title
Now showing items 17957-17976 of 18428
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Utilization of a Cloud-Based Diabetes Management Program for Insulin Initiation and Titration Enables Collaborative Decision Making Between Healthcare Providers and Patients
(Mary Ann Liebert, Inc., 2016)Abstract Background: Overseeing proper insulin initiation and titration remains a challenging task in diabetes care. Recent advances in mobile technology have enabled new models of collaborative care between patients and ... -
Utilization of a Mobile Medical Van for Delivering Pediatric Care in the Bateys of the Dominican Republic
(Springer-Verlag, 2010)Background Bateys are impoverished areas of housing for migrant Haitian sugar cane workers in the Dominican Republic (DR). In these regions, preventative health care is almost non-existent, public service accessibility is ... -
Utilization of a whole genome SNP panel for efficient genetic mapping in the mouse
(Cold Spring Harbor Laboratory Press, 2006)Phenotype-driven genetics can be used to create mouse models of human disease and birth defects. However, the utility of these mutant models is limited without identification of the causal gene. To facilitate genetic ... -
Utilization of Biomarker Data for Clinical and Environmental Intervention.
(1996)Of the 189 air toxics listed in the Clean Air Act, a substantial number are important in potentially causing adverse health effects in several organ systems. Although the major health effects are manifested as respiratory ... -
Utilization of mobile phones for accessing menstrual regulation services among low-income women in Bangladesh: a qualitative analysis
(BioMed Central, 2017)Background: As many as one-third of all pregnancies in Bangladesh are unplanned, with nearly one-half of these pregnancies ending in either menstrual regulation (MR) or illegal clandestine abortion. Although MR is provided ... -
Utilization of oral antidiabetic medications in Taiwan following strategies to promote access to medicines for chronic diseases in community pharmacies
(BioMed Central, 2015)Objectives: Taiwan’s National Health Insurance (NHI) has encouraged physicians to use “chronic medication prescriptions” for patients with stable chronic diseases since 1995. Patients are allowed to refill such prescriptions ... -
Utilization of the Safe Surgical Dislocation Approach of the Hip to Retrieve a Bullet from the Femoral Head
(Hindawi Publishing Corporation, 2011)Retained intra-articular missiles from low-velocity handguns can lead to mechanical arthritis, synovitis, and lead toxicity. Various surgical approaches have been described to extract such foreign bodies from the hip joint. ... -
Utilizing a handheld electrode array for localized muscle impedance measurements
(Wiley-Blackwell, 2012)Introduction: Electrical impedance myography (EIM) is a non-invasive technique used for assessment of muscle health in which a high-frequency, low-amplitude electric current is applied to the skin overlying a muscle, and ... -
Utilizing a Novel Giant Congenital Melanocytic Nevus Murine Model to Investigate Therapeutic Strategies and Model Tumorigenesis
(2017-05-12)Giant congenital melanocytic nevi (gCMN) are oncogene-driven proliferations of melanocytes present since birth that are greater than 20 cm in projected adult size, and have a melanoma conversion frequency of ranging from ... -
Utilizing a Personal Smartphone Custom App to Assess the Patient Health Questionnaire-9 (PHQ-9) Depressive Symptoms in Patients With Major Depressive Disorder
(JMIR Publications Inc., 2015)Background: Accurate reporting of patient symptoms is critical for diagnosis and therapeutic monitoring in psychiatry. Smartphones offer an accessible, low-cost means to collect patient symptoms in real time and aid in ... -
Utilizing ChatGPT in the Process of Crafting a Research Paper: A Comprehensive Guide
(Tan Tao University, 2023-08-22)The rapid advancement of artificial intelligence (AI) and natural language processing (NLP) technologies has paved the way for innovative tools, such as ChatGPT, to enhance various aspects of academic research. This ... -
Utilizing Fast Spin Echo MRI to Reduce Image Artifacts and Improve Implant/Tissue Interface Detection in Refractory Parkinson's Patients with Deep Brain Stimulators
(Hindawi Publishing Corporation, 2014)Introduction:. In medically refractory Parkinson's disease (PD) deep-brain stimulation (DBS) is an effective therapeutic tool. Postimplantation MRI is important in assessing tissue damage and DBS lead placement accuracy. ... -
Utilizing Nontraditional Data Sources for Near Real-Time Estimation of Transmission Dynamics During the 2015-2016 Colombian Zika Virus Disease Outbreak
(JMIR Publications, 2016)Background: Approximately 40 countries in Central and South America have experienced local vector-born transmission of Zika virus, resulting in nearly 300,000 total reported cases of Zika virus disease to date. Of the cases ... -
Utilizing Protein Degradation Platforms to Enhance CAR-T Cell Therapy
(2023-05-10)Background: Novel advances in cancer immunotherapy include “autonomous”, gene-modified cellular immunotherapies, that leverage genetic modifications to enhance expansion, dysfunction resistance, and effector function. ... -
Utilizing Targeted Gene Therapy with Nanoparticles Binding Alpha v Beta 3 for Imaging and Treating Choroidal Neovascularization
(Public Library of Science, 2011)Purpose: The integrin αvβ3 is differentially expressed on neovascular endothelial cells. We investigated whether a novel intravenously injectable αvβ3 integrin-ligand coupled nanoparticle (NP) can target choroidal neovascular ... -
UtpA and UtpB chaperone nascent pre-ribosomal RNA and U3 snoRNA to initiate eukaryotic ribosome assembly
(Nature Publishing Group, 2016)Early eukaryotic ribosome biogenesis involves large multi-protein complexes, which co-transcriptionally associate with pre-ribosomal RNA to form the small subunit processome. The precise mechanisms by which two of the ... -
UV fluorescence excitation imaging of healing of wounds in skin: Evaluation of wound closure in organ culture model
(John Wiley and Sons Inc., 2016)Background and Objective Molecules native to tissue that fluoresce upon light excitation can serve as reporters of cellular activity and protein structure. In skin, the fluorescence ascribed to tryptophan is a marker of ... -
UV hyper-resistance in Prochlorococcus MED4 results from a single base pair deletion just upstream of an operon encoding nudix hydrolase and photolyase
(Blackwell Publishing Ltd, 2010)Exposure to solar radiation can cause mortality in natural communities of pico-phytoplankton, both at the surface and to a depth of at least 30 m. DNA damage is a significant cause of death, mainly due to cyclobutane ... -
UV signaling pathways within the skin
(2014)The effects of UVR on the skin include tanning, carcinogenesis, immunomodulation, and synthesis of vitamin D, among others. Melanocortin 1 receptor polymorphisms correlate with skin pigmentation, UV sensitivity, and skin ... -
UV-A Irradiation Activates Nrf2-Regulated Antioxidant Defense and Induces p53/Caspase3-Dependent Apoptosis in Corneal Endothelial Cells
(The Association for Research in Vision and Ophthalmology, 2016)Purpose To examine whether Nrf2-regulated antioxidant defense and p53 are activated in human corneal endothelial cells (CEnCs) by environmental levels of ultraviolet A (UV-A), a known stimulator of oxidative stress. Methods: ...