Browsing Harvard Medical School by Title
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The Food and Drug Administration's Deliberations on Antidepressant Use in Pediatric Patients
(American Academy of Pediatrics (AAP), 2005)On February 2, 2004, the Food and Drug Administration organized a joint meeting of the Neuro-Psychopharmacologic Advisory Committee and Pediatric Subcommittee of the Anti-Infective Drugs Advisory Committee to examine the ... -
Food Assistance is Associated with Improved Body Mass Index, Food Security and Attendance at Clinic in an HIV Program in Central Haiti: A Prospective Observational Cohort Study
(BioMed Central, 2010)Background: Few data are available to guide programmatic solutions to the overlapping problems of undernutrition and HIV infection. We evaluated the impact of food assistance on patient outcomes in a comprehensive HIV ... -
Food Insecurity Among Homeless and Marginally Housed Individuals Living with HIV/AIDS in San Francisco
(Springer Verlag, 2009)Food insecurity is a risk factor for both HIV transmission and worse HIV clinical outcomes. We examined the prevalence of and factors associated with food insecurity among homeless and marginally housed HIV-infected ... -
Food Insecurity and Body Mass Index: A Longitudinal Mixed Methods Study, Chelsea, Massachusetts, 2009–2013
(Centers for Disease Control and Prevention, 2015)Introduction: Cross-sectional studies show an association between food insecurity and higher body mass index (BMI), but this finding has not been evaluated longitudinally. Patient perspectives on food choice in ... -
Food Insecurity and Cardiovascular Health in Pregnant Women: Results From the Food for Families Program, Chelsea, Massachusetts, 2013–2015
(Centers for Disease Control and Prevention, 2016)Background: Food insecurity, uncertainty about the ability to acquire adequate food, is associated with cardiometabolic disease in pregnant women. Whether food insecurity interventions improve cardiometabolic health is ... -
Food Insecurity and Metabolic Control Among U.S. Adults With Diabetes
(American Diabetes Association, 2013)OBJECTIVE We sought to determine whether food insecurity is associated with worse glycemic, cholesterol, and blood pressure control in adults with diabetes. RESEARCH DESIGN AND METHODS We conducted a cross-sectional analysis ... -
Food Insecurity as a Barrier to Sustained Antiretroviral Therapy Adherence in Uganda
(Public Library of Science, 2010)Background: Food insecurity is emerging as an important barrier to antiretroviral (ARV) adherence in sub-Saharan Africa and elsewhere, but little is known about the mechanisms through which food insecurity leads to ARV ... -
Food Predictors of Plasma Carotenoids
(MDPI, 2013)Empirical prediction models that weight food frequency questionnaire (FFQ) food items by their relation to nutrient biomarker concentrations may estimate nutrient exposure better than nutrient intakes derived from food ... -
Foot Disorders, Foot Posture, and Foot Function: The Framingham Foot Study
(Public Library of Science, 2013)Introduction: Foot disorders are common among older adults and may lead to outcomes such as falls and functional limitation. However, the associations of foot posture and foot function to specific foot disorders at the ... -
Foot Muscle Energy Reserves in Diabetic Patients Without and With Clinical Peripheral Neuropathy
(American Diabetes Association, 2009)Objective: To investigate changes in the foot muscle energy reserves in diabetic non-neuropathic and neuropathic patients. Research Design and Methods: We measured the phosphocreatinine (PCr)/inorganic phosphate (Pi) ratio, ... -
Foot Pressure Distribution During Walking in Young and Old Adults
(BioMed Central, 2005)Background: Measurement of foot pressure distribution (FPD) is clinically useful for evaluation of foot and gait pathologies. The effects of healthy aging on FPD during walking are not well known. This study evaluated FPD ... -
Forced Hepatic Overexpression of CEACAM1 Curtails Diet-Induced Insulin Resistance
(American Diabetes Association, 2015)Carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1) regulates insulin sensitivity by promoting hepatic insulin clearance. Liver-specific inactivation or global null-mutation of Ceacam1 impairs hepatic insulin ... -
Foreign DNA capture during CRISPR–Cas adaptive immunity
(2015)Bacteria and archaea generate adaptive immunity against phages and plasmids by integrating foreign DNA of specific 30–40 base pair (bp) lengths into clustered regularly interspaced short palindromic repeats (CRISPR) loci ... -
The Forest for the Trees: Using Big Data to Improve Preoperative Assessment and Risk Stratification in Pediatric Orthopedic Surgery
(2017-05-12)This thesis uses the Kid’s Inpatient Database to analyze surgical epidemiology, clinical outcomes, LOS, and total costs for two major pediatric surgeries. The goal is to establish clinically meaningful identifiers of risk, ... -
“Fork and bracket” syndrome expands the spectrum of SBF1-related sensory motor polyneuropathies
(Wolters Kluwer, 2016)Charcot-Marie-Tooth neuropathy type 4 (CMT4) comprises a large group of genetically heterogeneous progressive sensory motor neuropathies characterized by autosomal recessive inheritance. Among these, CMT4B includes 3 forms ... -
The Forkhead Transcription Factor Foxi1 Is a Master Regulator of Vacuolar H\(^+\)-ATPase Proton Pump Subunits in the Inner Ear, Kidney and Epididymis
(Public Library of Science, 2009)The vacuolar H\(^+\)-ATPase dependent transport of protons across cytoplasmic membranes in FORE (forkhead related) cells of endolymphatic epithelium in the inner ear, intercalated cells of collecting ducts in the kidney ... -
Forkhead Transcription Factors (FoxOs) Promote Apoptosis of Insulin-Resistant Macrophages During Cholesterol-Induced Endoplasmic Reticulum Stress
(American Diabetes Association, 2008)OBJECTIVE—Endoplasmic reticulum stress increases macrophage apoptosis, contributing to the complications of atherosclerosis. Insulin-resistant macrophages are more susceptible to endoplasmic reticulum stress–associated ... -
Formation of a DNA Loop at the Replication Fork Generated by Bacteriophage T7 Replication Proteins
(American Society for Biochemistry and Molecular Biology, 1998)Intermediates in the replication of circular and linear M13 double-stranded DNA by bacteriophage T7 proteins have been examined by electron microscopy. Synthesis generated double-stranded DNA molecules containing a single ... -
Formation of the factory matrix is an important, though not a sufficient function of nonstructural protein μNS during reovirus infection
(SAGE Publications, 2008)Genome replication of mammalian orthoreovirus (MRV) occurs in cytoplasmic inclusion bodies called viral factories. Nonstructural protein mu NS, encoded by genome segment M3, is a major constituent of these structures. When ... -
Formation of the Postmitotic Nuclear Envelope from Extended ER Cisternae Precedes Nuclear Pore Assembly
(The Rockefeller University Press, 2011)During mitosis, the nuclear envelope merges with the endoplasmic reticulum (ER), and nuclear pore complexes are disassembled. In a current model for reassembly after mitosis, the nuclear envelope forms by a reshaping of ...