Browsing Harvard Medical School by Keyword "Abstracts—September 10, 2013 (Day 3)"

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    • 136 HIV-1 Nef regulates activity of endoplasmic reticulum chaperone calnexin 

      Jennelle, Lucas; Hunegnaw, Ruth; Dubrovsky, Larisa; Pushkarsky, Tatiana; Fitzgerald, Michael L.; Sviridov, Dmitri; Bukrinsky*, Michael (JAIDS Journal of Acquired Immune Deficiency Syndromes, 2014)
      HIV-1 Nef promotes viral replication by downmodulating a number of cell surface transmembrane proteins, such as CD4, MHC-I and MHC-II, which are targeted by Nef to various degradation pathways. Nef is also responsible for ...