Browsing Harvard Medical School by Keyword "TNFR2"
Now showing items 1-1 of 1
-
Strategic internal covalent cross-linking of TNF produces a stable TNF trimer with improved TNFR2 signaling
(BioMed Central, 2015)Background: Soluble TNF superfamily (TNFSF) ligands are less stable and less active than their transmembrane (tm) analogues. This is a problem for the therapeutic use of recombinant TNFSF ligands in diverse diseases including ...