Browsing Harvard Medical School by Keyword "Ucn3"
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Reversal of β cell de-differentiation by a small molecule inhibitor of the TGFβ pathway
(eLife Sciences Publications, Ltd, 2014)Dysfunction or death of pancreatic β cells underlies both types of diabetes. This functional decline begins with β cell stress and de-differentiation. Current drugs for type 2 diabetes (T2D) lower blood glucose levels but ...