Browsing Harvard Medical School by Keyword "animal types"
Now showing items 1-2 of 2
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CNS Penetration of Intrathecal-Lumbar Idursulfase in the Monkey, Dog and Mouse: Implications for Neurological Outcomes of Lysosomal Storage Disorder
(Public Library of Science, 2012)A major challenge for the treatment of many central nervous system (CNS) disorders is the lack of convenient and effective methods for delivering biological agents to the brain. Mucopolysaccharidosis II (Hunter syndrome) ... -
Ligation of the Jugular Veins Does Not Result in Brain Inflammation or Demyelination in Mice
(Public Library of Science, 2012)An alternative hypothesis has been proposed implicating chronic cerebrospinal venous insufficiency (CCSVI) as a potential cause of multiple sclerosis (MS). We aimed to evaluate the validity of this hypothesis in a controlled ...