Browsing Harvard Medical School by Keyword "antiangiogenesis therapy"

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    • Resistance of Renal Cell Carcinoma to Sorafenib Is Mediated by Potentially Reversible Gene Expression 

      Bhasin, Manoj; Schor-Bardach, Rachel; Collins, Michael P.; Zhang, Liang; Wang, Xiaoen; Panka, David Joel; Putheti, Prabhakar; Signoretti, Sabina; Alsop, David C.; Libermann, Towia Aron; Atkins, Michael B.; Mier, James W.; Goldberg, S. Nahum; Bhatt, Rupal Satish (Public Library of Science, 2011)
      Purpose: Resistance to antiangiogenic therapy is an important clinical problem. We examined whether resistance occurs at least in part via reversible, physiologic changes in the tumor, or results solely from stable genetic ...