Browsing Harvard Medical School by Keyword "ASC-dependent inflammasome"
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Plasticity in PYD assembly revealed by cryo-EM structure of the PYD filament of AIM2
(2015)Absent in melanoma 2 (AIM2) is an essential cytosolic double-stranded DNA receptor that assembles with the adaptor, apoptosis-associated speck-like protein containing a caspase recruitment domain (ASC), and caspase-1 to ...