Browsing Harvard Medical School by Keyword "Acute kidney injury"

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    • Acute kidney injury subphenotypes based on creatinine trajectory identifies patients at increased risk of death 

      Bhatraju, Pavan K.; Mukherjee, Paramita; Robinson-Cohen, Cassianne; O’Keefe, Grant E.; Frank, Angela J.; Christie, Jason D.; Meyer, Nuala J.; Liu, Kathleen D.; Matthay, Michael A.; Calfee, Carolyn S.; Christiani, David C.; Himmelfarb, Jonathan; Wurfel, Mark M. (BioMed Central, 2016)
      Background: Acute kidney injury (AKI) is common among intensive care unit (ICU) patients. AKI is highly heterogeneous, with variable links to poor outcomes. Current approaches to classify AKI severity and identify patients ...

    • Meclizine Preconditioning Protects the Kidney Against Ischemia–Reperfusion Injury 

      Kishi, Seiji; Campanholle, Gabriela; Gohil, Vishal M.; Perocchi, Fabiana; Brooks, Craig R.; Morizane, Ryuji; Sabbisetti, Venkata; Ichimura, Takaharu; Mootha, Vamsi K.; Bonventre, Joseph V. (Elsevier, 2015)
      Global or local ischemia contributes to the pathogenesis of acute kidney injury (AKI). Currently there are no specific therapies to prevent AKI. Potentiation of glycolytic metabolism and attenuation of mitochondrial ...