Browsing Harvard Medical School by Keyword "Adoptive cell therapy"

Now showing items 1-2 of 2

    • Anti-KIT designer T cells for the treatment of gastrointestinal stromal tumor 

      Katz, Steven C; Burga, Rachel A; Naheed, Seema; Licata, Lauren A; Thorn, Mitchell; Osgood, Doreen; Nguyen, Cang T; Espat, N Joseph; Fletcher, Jonathan A.; Junghans, Richard P (BioMed Central, 2013)
      Background: Imatinib mesylate is an effective treatment for metastatic gastrointestinal stromal tumor (GIST). However, most patients eventually develop resistance and there are few other treatment options. Immunotherapy ...

    • Catch me if you can: Leukemia Escape after CD19-Directed T Cell Immunotherapies 

      Ruella, Marco; Maus, Marcela V. (Research Network of Computational and Structural Biotechnology, 2016)
      Immunotherapy is the revolution in cancer treatment of this last decade. Among multiple approaches able to harness the power of the immune system against cancer, T cell based immunotherapies represent one of the most ...